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Prevalence of and Risk Factors for Oral Human Papillomavirus Infection With Multiple Genotypes in the United States. | LitMetric

Prevalence of and Risk Factors for Oral Human Papillomavirus Infection With Multiple Genotypes in the United States.

Sex Transm Dis

From the *Department of Family and Preventative Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, OK; †Department of Epidemiology, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX; ‡Department of Epidemiology and Biostatistics, College of Public Health, The University of Georgia, Athens, GA; § Division of Quantitative Sciences, Department of Biostatistics, and ¶ Division of Surgery, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX.

Published: March 2017

AI Article Synopsis

  • This study examined the prevalence and risk factors for oral human papillomavirus (HPV) infections in the United States, focusing on multiple genotypes in a large sample size.
  • It found that overall, 1.5% of participants had multitype oral HPV infections, with higher rates among men and those with prior oral HPV positivity.
  • Key risk factors for increased multitype oral HPV infection included being male, being a current smoker, and having a new sexual partner in the past year.

Article Abstract

Background: This study investigated the prevalence of and risk factors for oral human papillomavirus (HPV) infection with multiple genotypes in the United States.

Methods: Data were from the nationally representative 2009-2012 National Health and Nutrition Examination Survey. This analysis comprised 9257 participants for whom data on oral HPV (37 genotypes) and associated risk factors were available.

Results: The weighted prevalence of multitype (2-6 types) oral HPV infection was 1.5% (2.5% for men, 0.4% for women) in the whole sample and 19.7% (22.0% for men, 12.1% for women) in those who had any type of oral HPV positivity. Most multitype oral HPV cases (83.8%) harbored one or more oncogenic types. In the adjusted multinominal logistic regression model, being male (relative risk ratio [RRR] = 3.69; 95% confidence interval [CI], 1.57-8.65), being a current cigarette smoker (RRR = 2.57; 95% CI, 1.23-5.36), and having a new sex partner in the past year (RRR = 2.10; 95% CI, 1.03-4.28) were associated with an increased risk of multitype oral HPV infection over single-type HPV infection.

Conclusions: Men, smokers, and those who had new sexual partners were at a significantly higher risk for multitype oral HPV infection.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710830PMC
http://dx.doi.org/10.1097/OLQ.0000000000000563DOI Listing

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