The concomitant presence of two zymodemes of the leishmania infantum complex. MON-1 and MON-77, is reported in a dog with diffuse leishmaniasis. The zymodemes were present in both the skin and lymph nodes. Possible explanations for the presence of the two zymodemes are discussed.
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http://dx.doi.org/10.1051/parasite/1989644312 | DOI Listing |
Unlabelled: Macrophages are the principal host cells of . in human infection and play a critical role in controlling infection and enabling parasite survival and persistence. Nevertheless, understanding of drug resistance in leishmaniasis has primarily focused on the parasite.
View Article and Find Full Text PDFPLoS Negl Trop Dis
May 2024
Centro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia.
Am J Trop Med Hyg
January 2024
Indian Council of Medical Research-Vector Control Research Centre, Puducherry, India.
The tribal population in and around the Western Ghats region of India is affected by both cutaneous leishmaniasis (CL) and visceral leishmaniasis (VL) with typical clinical symptoms. In this study, we recorded and analyzed seven CL and three VL cases from this emerging belt. All the cases were found as autochthonous transmission.
View Article and Find Full Text PDFParasitology
February 2024
Secció de Parasitologia, Departament Biologia, Sanitat i Medi Ambient, Facultat Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Barcelona, Spain.
In 2009, a large outbreak of leishmaniasis, associated with environmental changes, was declared near Madrid (Spain), in which was the vector, whereas the main reservoirs were hares and rabbits. Analysis of isolates from humans, vectors and leporids from the focus identified the ITS-Lombardi genotype. However, multilocus enzyme electrophoresis (MLEE), the reference technique for typing, and sequencing of the gene, a commonly used marker, were not performed.
View Article and Find Full Text PDFParasit Vectors
August 2023
Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, PU, Italy.
Background: Leishmaniasis is a zoonotic disease endemic in the Mediterranean region where Leishmania infantum is the causative agent of human and canine infection. Characterization of this parasite at the subspecies level can be useful in epidemiological studies, to evaluate the clinical course of the disease (e.g.
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