AI Article Synopsis
- The study evaluates EQA schemes by comparing results to established target values using robust statistical methods.
- Outliers were removed, and the mean or median was used as a target value based on the distributions.
- The results showed that the target values and Roche’s calibration values had comparable performance metrics, with high rates of acceptable performance.
Article Abstract
Background: In EQA schemes, results are usually assessed against a target value.
Methods: Outliers in each result were deleted using a robust statistical method. Mean was used as a target value if trimmed results were normally distributed; otherwise, median was used. Differences between target value and Roche's calibration value were calculated. Rates of acceptable performance evaluated by target value and Roche's calibration value were determined.
Results: Target values of P, GLU, urea, UA, TP, ALB, TC, TG, ALT, AST, ALP, AMY, LDH, GGT, FE, and HBDH were 1.70 mmol/L, 11.0 mmol/L, 16.8 mmol/L, 307 μmol/L, 54.0 g/L, 38.1 g/L, 4.19 mmol/L, 1.46 mmol/L, 97.7 U/L, 98.2 U/L, 206 U/L, 180 U/L, 242 U/L, 115 U/L, 35.6 μmol/L, and 255 U/L, respectively. Differences between target values and Roche's calibration values were -3.45 to 1.48%. Rates of acceptable performance evaluated by target values and Roche's calibration values were 96.5 - 100.0% and 93.0 - 100.0%, respectively.
Conclusions: Target values established using a robust statistical method and Roche's calibration values were comparable.
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Source |
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| http://dx.doi.org/10.7754/Clin.Lab.2016.160227 | DOI Listing |
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