AI Article Synopsis
- - The study discusses a case of an 82-year-old immunodeficient man who suffered from venous thromboembolism, which was caused by compression of the iliac vein.
- - Traditional treatment with vein stenting was avoided due to the patient's compromised immune system, and instead, a new approach was taken using a single-dose of edoxaban.
- - After three months of this treatment, the patient's thrombus was completely resolved, marking this as the first report of effective use of direct oral anticoagulants in similar cases without the need for injections.
Article Abstract
Background: Although vein stenting is popular for treatment for venous thromboembolism due to mechanical compression, some cases are forced to avoid inserting align agents because of immunodeficiency.
Case Presentation: An 82-year-old man with left extremity redness and swelling presented to a hospital for a medical evaluation. The patient was immunodeficient because of the adverse effects of his treatment for Castleman's disease. A contrast-enhanced computed tomography scan revealed a venous thromboembolism in inferior vena cava and the left lower extremity. Magnetic resonance venography showed that the iliac artery was compressing the iliac vein. We were reluctant to place a stent in the iliac vein has because of the patient's immunodeficient status. Three months of treatment using single-dose edoxaban (30 mg daily) resulted in complete resolution of the thrombus. This is the first report demonstrating that single-dose edoxaban without acute-phase parenteral anticoagulation is effective in the treatment of iliac vein compression.
Conclusions: A single-dose direct oral anti-coagulant without acute-phase parenteral anticoagulation is effective for mechanical compression.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286566 | PMC |
| http://dx.doi.org/10.1186/s12959-017-0128-2 | DOI Listing |
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