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Total Serum Immunoglobulin E in a Cohort of Children with Food Allergy.
J Allergy Clin Immunol Pract
December 2024
Division of Biostatistics and Epidemiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, College of Medicine, Cincinnati, OH; Division of Asthma Research, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, College of Medicine, Cincinnati, OH.
Background: Total serum immunoglobulin E (TsIgE) has not been examined in children with food allergy.
Objective: Evaluate associations of TsIgE with patient, household, environmental and community-level characteristics among children with food allergy.
Method: Linear mixed effect models of data from 398 Black and/or African American (B/AA) and White and/or European American (W/EA) children with allergist-diagnosed food allergy from the multi-center, observational cohort FORWARD; TsIgE in kU/L was the primary outcome measure.
Demographic characteristics associated with a penicillin allergy label during pregnancy.
Front Allergy
December 2024
Section of Allergy and Immunology, Division of Pulmonary, Allergy and Critical Care Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Introduction: Penicillins and other beta-lactam antibiotics are used in greater than one-third of pregnant women as treatment for Group B Streptococcus colonization and prophylaxis for Caesarean sections. Penicillin allergy labels have been associated with increased morbidity in the pregnant population, and penicillin allergy evaluation during pregnancy is now recognized as safe and effective. Yet, demographic characteristics associated with having a penicillin allergy label during pregnancy have not been studied.
View Article and Find Full Text PDFAssociation between atopic dermatitis with hyperparathyroidism not mediated by vitamin D in the United States (NHANES 2005-2006).
Arch Dermatol Res
December 2024
Department of Dermatology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Zhejiang Provincial Hospital of Chinese Medicine), No. 54 Youdian Road, Hangzhou, 310006, Zhejiang, China.
The association between atopic eczema and hyperparathyroidism remains doubtful. Participants with atopic dermatitis have lower serum vitamin D levels. Whether it is mediated by vitamin D or other potential factors remains uncertain as well.
View Article and Find Full Text PDFUpdated consensus guidelines for management of moderate-to-severe atopic dermatitis in Singapore: Integrating biologics, Janus kinase inhibitors and conventional therapies.
Ann Acad Med Singap
November 2024
Department of Dermatology, Singapore General Hospital, Singapore.
Article Synopsis
- Several new therapies, including biologics and JAK inhibitors, have been approved for treating atopic dermatitis (AD) in Singapore since 2016, leading to an update of treatment guidelines for moderate-to-severe cases.
- A modified Delphi panel with 12 dermatologists conducted surveys to reach consensus on treatment statements, resulting in agreement on 43 statements across different treatment categories.
- The study highlights dupilumab and JAK inhibitors as potential first-line treatments for certain patients with moderate-to-severe AD, and indicates that further updates to the guidelines may be necessary as new information emerges.
Unveiling the Impact of Moderate and Severe Atopic Dermatitis: Insights on Burden, Clinical Characteristics, and Healthcare Resource Utilization in Adult Greek Patients from the APOLO Cross-Sectional Study.
J Clin Med
October 2024
Pfizer Hellas SA, 15451 Neo Psichiko, Greece.
Article Synopsis
- * A study in Greece involved 184 adults, revealing that many suffer from additional issues like obesity and allergic comorbidities, with the majority receiving specific treatment for their condition.
- * Key findings included high rates of pain, severe itching, and sleep disturbances, with patients reporting substantial reductions in work productivity and overall well-being.
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