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Purpose: The aim of this study was to review the epidemiology and clinical outcomes of open-globe injuries (OGIs) in Hong Kong over a 10-year period.
Design: Retrospective case-review.
Methods: This study included patients with OGI who presented to Hong Kong Eye Hospital and Queen Elizabeth Hospital from 1999 to 2008. Patient demographics, causes and mechanisms of injury, visual acuity (VA) at presentation, clinical features, and final VA were collected. Univariate and multivariate analyses using logistic regression were performed to identify poor prognostic factors.
Results: A total of 122 eyes of 121 patients were included. More than half (63%) were male, and the mean age was 54 years. Workplace injuries (36%) ranked first, followed by fall (32%) and assault (13%). The majority (66%) presented with VA less than 5/200. Common associations included hyphema, lens damage, uveal prolapse, and vitreous hemorrhage. Overall, about half (46%) sustained profound visual loss (final VA <5/200). Twelve eyes underwent evisceration or enucleation. Only 1 eye developed endophthalmitis. Univariate analysis suggested that profound visual loss was associated with poor initial VA, relative afferent pupillary defect, and posterior scleral involvement (P < 0.05). Multivariate analysis showed that poor initial VA and posterior involvement were independent poor prognostic factors.
Conclusions: Profound visual loss was common after OGIs, especially in cases with poor vision at presentation and involvement of the posterior sclera. Identifying poor prognostic factors helps guide clinical management and facilitates counseling for patients. Early medical and surgical treatment may help to reduce the risk of endophthalmitis.
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http://dx.doi.org/10.1097/APO.0000000000000211 | DOI Listing |
Worldviews Evid Based Nurs
April 2025
Department of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
Background: Previous studies regarding mind-body exercise among people with breast cancer mostly focused on one type of mind-body exercise and provided conflicting results.
Aims: This paper aims to systematically synthesize the evidence hierarchy and examine the credibility of previous meta-analyses of different types of mind-body exercises.
Methods: We searched PubMed, Embase, Cochrane Library, Web of Science, and Epitemonikos from database inception to February 2nd, 2024, for meta-analyses of randomized controlled trials.
Ultrasonics
May 2025
Department of Building Environment and Energy Engineering, The Hong Kong Polytechnic University, Hong Kong, China; Division of Science, Engineering and Health Studies, College of Professional and Continuing Education, The Hong Kong Polytechnic University, Hong Kong, China. Electronic address:
SAW (surface acoustic wave)-based microfluidics is fast becoming a recognised method for isolating and concentrating particles given its capacity for safe and label-free particle manipulation. However, widespread adoption of acoustofluidics for clinical and industrial applications is hindered by its limited capability handling submicron particles. Smaller particles, which are primarily influenced by the acoustic streaming effect, can be captured and enriched by streaming-induced vortices.
View Article and Find Full Text PDFThorax
March 2025
Department of Occupational & Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
Background: High-level exposure to crystalline silica dust is the key factor in silicosis. Long-term exposure to low-level silica dust, for example, lower than that in occupational exposure limits, still needs to be studied for their risk of silicosis.
Methods: A total of 30 697 workers were included from a cohort in China.
Neurosci Biobehav Rev
March 2025
State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong; Laboratory of Neuropsychology & Human Neuroscience, The University of Hong Kong, Hong Kong. Electronic address:
Metastability is proposed as the mechanism supporting our adaptive responses to the environment. While extensive research has characterized brain metastability during rest and task performance, prior studies have mainly focused on understanding underlying mechanisms, with limited exploration of its application in mental processes and behaviors. This scoping review offers an overview of the existing empirical literature in this area.
View Article and Find Full Text PDFLancet Respir Med
March 2025
World Health Emergencies Programme, WHO, Geneva, Switzerland. Electronic address:
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