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Identifying falsified COVID-19 vaccines by analysing vaccine vial label and excipient profiles using MALDI-ToF mass spectrometry.
NPJ Vaccines
January 2025
Department of Biochemistry, University of Oxford, OX1 3QU, Oxford, UK.
The rapid development and worldwide distribution of COVID-19 vaccines is a remarkable achievement of biomedical research and logistical implementation. However, these developments are associated with the risk of a surge of substandard and falsified (SF) vaccines, as illustrated by the 184 incidents with SF and diverted COVID-19 vaccines which have been reported during the pandemic in 48 countries, with a paucity of methods for their detection in supply chains. In this context, matrix-assisted laser desorption ionisation-time of flight (MALDI-ToF) mass spectrometry (MS) is globally available for fast and accurate analysis of bacteria in patient samples, offering a potentially accessible solution to identify SF vaccines.
View Article and Find Full Text PDFEnhanced multifaceted model for plasmon-driven Schottky solar cells with integrated thermal effects.
Sci Rep
January 2025
Department of Physics, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.
This paper explores the development of an opto-thermal-electrical model for plasmonic Schottky solar cells (PSSCs) using a comprehensive multiphysics approach. We simulated the optical properties, power conversion efficiencies, and energy yield of PSSCs with varying nanoparticle (NP) configurations and sizes. Our spectral analysis focused on the absorption characteristics of these solar cells, examining systems sized 3 × 3, 5 × 5, and 7 × 7, with NP radii ranging from 10 to 150 nm.
View Article and Find Full Text PDFSuperior energy storage capacity of polymer-based bilayer composites by introducing 2D ferroelectric micro-sheets.
Nat Commun
January 2025
School of Instrumentation Science and Engineering, Harbin Institute of Technology, Harbin, China.
Dielectric polymer capacitors suffer from low discharged energy density and efficiency due to their low breakdown strength, small dielectric constant and large electric hysteresis. Herein, a synergistic enhancement strategy is proposed to significantly increase both breakdown strength and dielectric constant while suppressing hysteresis, through introducing 2-dimensional bismuth layer-structured NaBiTiO micro-sheets and designing a unique bilayer structure. Excitingly, an ultra-high discharged energy density of 25.
View Article and Find Full Text PDFStrategies for Implementing Integrated Behavioral Health into Health Centers.
J Am Board Fam Med
January 2025
From the Center for State Health Policy, Rutgers University, New Brunswick, NJ (AMN); Henry J. Austin Health Center, Trenton, NJ (RAK); University of Illinois Chicago, School of Public Health, Chicago, IL (TM); Institute for Health, Healthcare Policy and Aging Research, Rutgers University, New Brunswick, NJ (CV); Rutgers University Behavioral Health Care, New Brunswick, NJ (SM); Department of Family Medicine and Community Health, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (BFC).
Background: Integrated behavioral health (IBH) is a promising approach which embeds behavioral health services into primary care. Yet, IBH has had limited implementation. Our objective was to identify strategies to successfully implement the "Cherokee" IBH model by examining a 2013 to 2019 IBH demonstration project in New Jersey that included Federally Qualified Health Centers (FQHCs) and Community Health Centers (CHCs).
View Article and Find Full Text PDFCSF-Venous Fistulas Arising Intraosseously within Bone Remodeled by Meningeal Diverticula.
AJNR Am J Neuroradiol
January 2025
Department of Radiology (M.D.M.), Permanente Medical Group, Kaiser Permanente Medical Center Santa Clara, Santa Clara, California.
CSF-venous fistulas (CVFs) are a common and increasingly recognized type of spinal CSF leak. Most of these fistulas occur in the setting of spontaneous intracranial hypotension, though nonspontaneous cases have been described as well. In most instances, CVFs arise from the dome or neck of nerve root sleeve diverticula (also called meningeal diverticula).
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