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http://dx.doi.org/10.1093/eurheartj/ehw632 | DOI Listing |
Sci Rep
January 2025
Yunnan Characteristic Plant Extraction Laboratory, Yunnan Yunke Characteristic Plant Extraction Laboratory Co., Ltd, Yunnan, 650106, China.
This study aimed to develop in vivo methods for assessing facial anti-glycation and anti-aging effects and to investigate the link between glycation and aging signs. We utilized an AGE reader to measure AGEs levels on the face and arms, establishing a correlation to validate the reader's use for facial AGEs detection. Then the product's 7-day anti-glycation effect was evaluated.
View Article and Find Full Text PDFBackground Low back pain (LBP) is a prevalent condition that significantly affects work productivity and quality of life. Despite advancements in treatment, LBP continues to pose a global health challenge, with increasing research on manipulative therapy as a non-invasive treatment option. This study aims to provide a comprehensive bibliometric analysis of global research trends in manipulative therapy for LBP.
View Article and Find Full Text PDFInsights Imaging
January 2025
Department of Radiology, the Second Affiliated Hospital of Dalian Medical University, Dalian, 116023, China.
Objective: To evaluate the feasibility of utilizing artificial intelligence (AI)-predicted biparametric MRI (bpMRI) image features for predicting the aggressiveness of prostate cancer (PCa).
Materials And Methods: A total of 878 PCa patients from 4 hospitals were retrospectively collected, all of whom had pathological results after radical prostatectomy (RP). A pre-trained AI algorithm was used to select suspected PCa lesions and extract lesion features for model development.
Funct Integr Genomics
January 2025
Department of Exercise Science and Health Promotion, Florida Atlantic University, Boca Raton, FL, USA.
Large-scale, pan-cancer analysis is enabled by data driven knowledge bases that link tumor molecular profiles with phenotypes. A debilitating cancer-related phenotype is skeletal muscle loss, or cachexia, which occurs partly from tumor products secreted into circulation. Using the LinkedOmicsKB knowledge base assembled from the Clinical Proteomics Tumor Analysis Consortium proteogenomic analysis, along with catalogs of human secretome proteins, ligand-receptor pairs and molecular signatures, we sought to identify candidate pan-cancer proteins secreted to blood that could regulate skeletal muscle phenotypes in multiple solid cancers.
View Article and Find Full Text PDFJ Bone Miner Res
January 2025
Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, United States.
Bone turnover assessment and monitoring are essential for chronic kidney disease (CKD)-associated bone care. Patients with CKD suffer from significantly elevated fracture risk due to abnormally high or low bone turnover, which requires diametrically opposite treatments informed by patient-specific bone turnover data. However, a reliable, accessible, non-invasive bone turnover assessment and monitoring tool remains an unmet clinical need.
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