When LIN41 Comes to a Fork in the Road, It Takes BOTH Paths: Translational Repression OR mRNA Decay, Depending on the Target Site Position.

Mol Cell

Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA; Department of Molecular and Integrative Physiology, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA. Electronic address:

Published: February 2017

In this issue, Aeschimann et al. (2017) demonstrate that, depending on the target location site (5'UTR or 3'UTR), LIN41 triggers repression of translation or mRNA decay, suggesting that one factor may use two independent pathways of post-transcriptional gene regulation.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2017.01.018DOI Listing

Publication Analysis

Top Keywords

mrna decay
8
depending target
8
lin41 fork
4
fork road
4
road takes
4
takes paths
4
paths translational
4
translational repression
4
repression mrna
4
decay depending
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!