[Pulmonary sarcoidosis presenting as multiple scattered pulmonary nodules: about a case].

Pan Afr Med J

Service de Médecine Interne, Hôpital Razi, la Manouba 2010, Faculté de Médecine de Tunis, Tunis Tunisie.

Published: February 2017

Sarcoidosis is a multisystem granulomatous disease that can affect all organs, thoracic involvement often predominates representing its most evocative manifestation. Atypical manifestations, such as the presence of multiple scattered pulmonary nodules may indicate malignancy. Our study reports the case of a 56-year-old patient investigated for asthenia associated with paresthesia of the lower limbs evolving since 6 months. Chest CT scan showed multiple scattered pulmonary nodules. Histological examination of specimens obtained by bronchial biopsy allowed to exclude neoplastic origin and confirmed the diagnosis of sarcoidosis. On the basis of normal pulmonary function tests and the absence of extrapulmonary visceral involvement, simple patient monitoring was recommended. Radiologically sarcoidosis can exceptionally present as multiple scattered pulmonary nodules. Histological evidence is necessary to exclude other etiologies including tumors. Corticosteroids are indicated only in the presence of severe respiratory functional impairment and/or associated visceral involvement.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267871PMC
http://dx.doi.org/10.11604/pamj.2016.24.295.7664DOI Listing

Publication Analysis

Top Keywords

multiple scattered
16
scattered pulmonary
16
pulmonary nodules
16
nodules histological
8
visceral involvement
8
pulmonary
5
[pulmonary sarcoidosis
4
sarcoidosis presenting
4
multiple
4
presenting multiple
4

Similar Publications

Trace detection of S. aureus cells in food samples via RCA-assisted SERS signal amplification with core-shell nanoprobe.

Talanta

December 2024

School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, PR China; College of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, PR China. Electronic address:

Staphylococcus aureus (S. aureus) has been identified as a indicator of food contamination. In this study, a sensitive and accurate biosensor strategy for S.

View Article and Find Full Text PDF

In this study, the improvement mechanism of yeast proteins (YPs) with the ultrasonic and pH shifting treatment on the emulsion stability was investigated through the solubility, protein structure and interface behavior of YPs. Compared with only pH shifting or ultrasound treatment, the solubility of YPs with the combined treatment of ultrasonic and pH shifting was increased significantly. The soluble protein content of pH-U400 reached 85.

View Article and Find Full Text PDF

Globally, heavy metal (HM) soil pollution is becoming an increasingly serious concern. Heavy metals in soils pose significant environmental and health risks due to their persistence, toxicity, and potential for bioaccumulation. These metals often originate from anthropogenic activities such as industrial emissions, agricultural practices, and improper waste disposal.

View Article and Find Full Text PDF

Shock waves, the interface of supersonic and subsonic plasma flows, are the primary region for charged particle acceleration in multiple space plasma systems, including Earth's bow shock, which is readily accessible for in-situ measurements. Spacecraft frequently observe relativistic electron populations within this region, characterized by energy levels surpassing those of solar wind electrons by a factor of 10,000 or more. However, mechanisms of such strong acceleration remain elusive.

View Article and Find Full Text PDF
Article Synopsis
  • The rising incidence of cancer has created a pressing need for improved early detection tools, highlighting the importance of identifying specific biomarkers for accurate diagnosis.
  • Cancer-derived small extracellular vesicles (sEVs) have emerged as a promising biomarker, given their abundance in body fluids and their rich assortment of biological indicators.
  • Surface-enhanced Raman scattering (SERS) technology is gaining traction for its ability to quickly and sensitively detect cancer sEVs using various innovative assays, paving the way for enhanced early detection and classification of cancers in clinical settings.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!