Sarcoidosis is a multisystem granulomatous disease that can affect all organs, thoracic involvement often predominates representing its most evocative manifestation. Atypical manifestations, such as the presence of multiple scattered pulmonary nodules may indicate malignancy. Our study reports the case of a 56-year-old patient investigated for asthenia associated with paresthesia of the lower limbs evolving since 6 months. Chest CT scan showed multiple scattered pulmonary nodules. Histological examination of specimens obtained by bronchial biopsy allowed to exclude neoplastic origin and confirmed the diagnosis of sarcoidosis. On the basis of normal pulmonary function tests and the absence of extrapulmonary visceral involvement, simple patient monitoring was recommended. Radiologically sarcoidosis can exceptionally present as multiple scattered pulmonary nodules. Histological evidence is necessary to exclude other etiologies including tumors. Corticosteroids are indicated only in the presence of severe respiratory functional impairment and/or associated visceral involvement.
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http://dx.doi.org/10.11604/pamj.2016.24.295.7664 | DOI Listing |
Talanta
December 2024
School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, PR China; College of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, PR China. Electronic address:
Staphylococcus aureus (S. aureus) has been identified as a indicator of food contamination. In this study, a sensitive and accurate biosensor strategy for S.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China. Electronic address:
In this study, the improvement mechanism of yeast proteins (YPs) with the ultrasonic and pH shifting treatment on the emulsion stability was investigated through the solubility, protein structure and interface behavior of YPs. Compared with only pH shifting or ultrasound treatment, the solubility of YPs with the combined treatment of ultrasonic and pH shifting was increased significantly. The soluble protein content of pH-U400 reached 85.
View Article and Find Full Text PDFSci Rep
January 2025
College of Jilin Emergency Management, Changchun Institute of Technology, Changchun, 130012, China.
Globally, heavy metal (HM) soil pollution is becoming an increasingly serious concern. Heavy metals in soils pose significant environmental and health risks due to their persistence, toxicity, and potential for bioaccumulation. These metals often originate from anthropogenic activities such as industrial emissions, agricultural practices, and improper waste disposal.
View Article and Find Full Text PDFNat Commun
January 2025
NASA Goddard Space Flight Center, Heliophysics Science Division, Greenbelt, MD, USA.
Shock waves, the interface of supersonic and subsonic plasma flows, are the primary region for charged particle acceleration in multiple space plasma systems, including Earth's bow shock, which is readily accessible for in-situ measurements. Spacecraft frequently observe relativistic electron populations within this region, characterized by energy levels surpassing those of solar wind electrons by a factor of 10,000 or more. However, mechanisms of such strong acceleration remain elusive.
View Article and Find Full Text PDFNanoscale
January 2025
School of Natural Sciences, Faculty of science and engineering, Macquarie University, Sydney, NSW 2109, Australia.
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