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| http://dx.doi.org/10.1073/pnas.1620731114 | DOI Listing |
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Intriguing tumor, synovial sarcoma: Hard to diagnose, harder to treat.
Orthop Traumatol Surg Res
January 2025
Ankara University Medical Faculty, İbni Sina Hospital, Department of Orthopedics and Traumatology, Talatpasa Boulevard no:82, 06630 Ankara, Turkey.
Background: Synovial sarcoma (SS) is classified as an aggressive high-grade soft tissue sarcoma that predominantly affects the extremities. Despite its prevalence in the extremities (up to 80%), diagnostic and treatment challenges persist. This study aims to address these challenges by providing a comprehensive analysis of SS in extremities, focusing on diagnostic accuracy and treatment outcomes.
View Article and Find Full Text PDFTextural Analysis of Sea Lamprey Muscle From Guadiana and Mondego Rivers (Portugal) Using the Warner-Bratzler Shear Method.
J Texture Stud
February 2025
MED-Mediterranean Institute for Agriculture, Environment and Development & CHANGE-Global Change and Sustainability Institute, Universidade de Évora, Évora, Portugal.
Assessment of sea lamprey texture from the Guadiana and Mondego River basins. Lamprey has served as food for centuries, and nowadays it is highly appreciated, mainly in southern European countries. Therefore, the quality requirements of the lamprey are closely scrutinized by consumers.
View Article and Find Full Text PDFGeneration of transgenic fish cell line with α-lactalbumin nanocarriers co-delivering Tol2 transposase mRNA and plasmids.
iScience
August 2024
Key Laboratory of Aquatic Genomics, Ministry of Agriculture and Rural Affairs and Beijing Key Laboratory of Fishery Biotechnology, Chinese Academy of Fishery Sciences, Beijing 100141, China.
Article Synopsis
- Fish cells, particularly grass carp kidney (CIK) cells, are more challenging to transfect compared to mammalian cells, necessitating a better gene delivery method.
- A novel nanocarrier made from α-lactalbumin (α-NC) was developed, showing effective absorption of nucleic acids and low toxicity, outperforming traditional liposomal transfection reagents.
- This system allowed for successful co-transfection of key genetic materials, resulting in a stable transgenic CIK cell line with integrated Cas9 and GFP, thus providing a streamlined approach for creating stable transgenic fish cell lines.
Influence of grain type and fat source on performance, nutrient utilization, and gut properties in broilers fed pelleted diets.
Poult Sci
October 2024
Monogastric Research Centre, School of Agriculture and Environment, Massey University, Palmerston North 4442, New Zealand; A2Z Poultry Feed DynamikZ, Villeurbanne 69100, France.
The influence of grain type and fat source on the performance, coefficient of apparent ileal digestibility (CAID), and intestinal characteristics in broiler starters fed pelleted diets were studied. The experiment included 8 treatments arranged as a 2 × 4 factorial with 2 grains (wheat and corn) and 4 fat sources (soybean oil, fish oil, tallow, and palm oil). In all fat sources, corn-fed birds had a higher weight gain than those fed wheat-based diets.
View Article and Find Full Text PDFInterneuron diversity in the human dorsal striatum.
Nat Commun
July 2024
Karolinska Institutet, Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Stockholm, Sweden.
Deciphering the striatal interneuron diversity is key to understanding the basal ganglia circuit and to untangling the complex neurological and psychiatric diseases affecting this brain structure. We performed snRNA-seq and spatial transcriptomics of postmortem human caudate nucleus and putamen samples to elucidate the diversity and abundance of interneuron populations and their inherent transcriptional structure in the human dorsal striatum. We propose a comprehensive taxonomy of striatal interneurons with eight main classes and fourteen subclasses, providing their full transcriptomic identity and spatial expression profile as well as additional quantitative FISH validation for specific populations.
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