Alashinols F and G, two lignans from stem bark of Syringa pinnatifolia.

Nat Prod Res

a Modern Research Center for Traditional Chinese Medicine , Beijing University of Chinese Medicine, Beijing , People's Republic of China.

Published: July 2017

AI Article Synopsis

  • Two new lignans, alashinols F and G, were discovered in the stem bark of Syringa pinnatifolia, a plant used in Mongolian medicine.
  • Their structures were determined using various analytical techniques, including mass spectrometry and NMR.
  • The study also explored the compounds' potential effects against inflammation and hypoxia in lab settings.

Article Abstract

Two new lignans, alashinols F and G (1 and 2), together with two known analogues (-)-secoisolariciresinol (3) and meso-secoisolariciresinol (4) were isolated from the stem bark of Syringa pinnatifolia, a Mongolian folk medicine with anti-myocardial ischaemic effects. Their structures were elucidated on basis of spectroscopic data analyses, including MS and 1D and 2D NMR, and their absolute configurations were elucidated on the basis of experimental and calculated electronic circular dichroisms. The in vitro anti-inflammation and anti-hypoxia evaluations were also discussed.

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Source
http://dx.doi.org/10.1080/14786419.2017.1283500DOI Listing

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