A total of 143 pregnant women aged 17 to 45 years were investigated and treated at 12-th to 40-th weeks of gestation. All patients underwent dental interventions under combined anesthesia: premedication (seduxen, 0.1 to 0.2 mg/kg body weight, eventually combined with metacin, 0.5 to 1 mg/kg, and baralgin, 20 to 30 mg/kg) and local anesthesia with 1% trimecaine-epinephrine solution. The adequacy of premedication was evaluated using psychological testing, recording the cardiotachogram and transcutaneous PO2. In 23 patients somatosensory evoked potentials (SEP) to dental pulp stimulation were also recorded. The fetal functional state was simultaneously assessed using cardiotachography.

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