A 62 year old male patient had disseminated discoid lupus erythematosus and multiple nodules over the sun-exposed areas which were diagnosed as multiple keratoacanthomas. Nodules were asymptomatic and had a warty surface covered with thick scales.
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J Dent Sci
January 2025
Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background/purpose: Discoid lupus erythematosus (DLE) serves as an interdisciplinary disease involved in dermatology and stomatology in many cases. The purpose of this study was to analyze the scientometric characteristics and research trends of DLE.
Materials And Methods: All the papers on DLE were comprehensively retrieved from the Scopus database.
Cureus
December 2024
Emergency and Accident, District Headquarter Hospital, Jhelum Valley, Muzaffarabad, PAK.
This retrospective study analyzes the histopathological patterns of skin lesions in 430 patients with systemic lupus erythematosus (SLE), meeting the American College of Rheumatology criteria from 2018-2023. Patient demographics reveal a mean age of 43.56 years, with a near-equal gender distribution (50.
View Article and Find Full Text PDFPharmaceutics
January 2025
Department of Dermatology, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.
Phosphodiesterase-4 (PDE4) is involved in the synthesis of inflammatory cytokines that mediate several chronic inflammatory disorders, including psoriasis and atopic dermatitis. In recent years, the therapeutic armamentarium in dermatology has expanded with the introduction of PDE4 inhibitors, both in oral and topical formulations. PDE4 inhibitors have gained increasing interest due to their remarkable safety record and ease of prescription, as evidenced by the recent influx of literature detailing its off-label uses.
View Article and Find Full Text PDFDermatol Pract Concept
January 2025
Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania, Naples, Italy.
Introduction: Previous studies have investigated the density of dermal papillae (DP) in normal skin using reflectance confocal microscopy (RCM), a non-invasive imaging technique that allows a real time, high-resolution imaging of the skin, although no histological confirmation was provided. The aim of the present study was to compare the RCM evaluation of DP density in healthy skin with horizontal histopathological sections (HHS), a technique that provides a horizontal view of the skin.
Methods: Ten adult patients were selected, and a healthy skin area was marked for RCM examination and a subsequent 5-mm punch biopsy that was processed for HHS.
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