Bloodstream infections and antimicrobial sensitivity patterns in a tertiary care hospital of India.

Ther Adv Infect Dis

National Institute of Medical Sciences & Research, NIMS University, Jaipur, India.

Published: October 2016

Background: Invasion of the bloodstream by microorganisms constitutes one of the most serious situations in infectious disease. Microorganisms present in circulating blood whether continuously, intermittently, or transiently are a threat to every organ in the body. Prevalence and antimicrobial susceptibility of microorganisms vary depending upon the geography and the use of antibiotics.

Methods: A cross-sectional study to determine the prevalent organisms causing bloodstream infection was conducted. BACTEC BD 9050 system was used to identify the causative organism, and sub-cultures were done on MacConkey Agar and Blood Agar. Antibiotic susceptibility test (AST) was done using Kirby B Disk diffusion method.

Results: A total of 170 patients were enrolled, and blood samples of 53 patients showed growth of organisms. was the most commonly isolated organism. Most of the Gram-positive cocci (GPC) were susceptible to vancomycin and linezolid. Most of the Gram-negative bacilli (GNB) showed sensitivity to cefoperazone/sulbactam followed by imipenem.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256192PMC
http://dx.doi.org/10.1177/2049936116666983DOI Listing

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