Rapid population growth of major urban centres in many developing countries has created massive landfills with extraordinary heights and steep side-slopes, which are frequently surrounded by illegal low-income residential settlements developed too close to landfills. These extraordinary landfills are facing high risks of catastrophic failure with potentially large numbers of fatalities. This study presents a novel method for risk assessment of landfill slope failure, using probabilistic analysis of potential failure scenarios and associated fatalities. The conceptual framework of the method includes selecting appropriate statistical distributions for the municipal solid waste (MSW) material shear strength and rheological properties for potential failure scenario analysis. The MSW material properties for a given scenario is then used to analyse the probability of slope failure and the resulting run-out length to calculate the potential risk of fatalities. In comparison with existing methods, which are solely based on the probability of slope failure, this method provides a more accurate estimate of the risk of fatalities associated with a given landfill slope failure. The application of the new risk assessment method is demonstrated with a case study for a landfill located within a heavily populated area of New Delhi, India.
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http://dx.doi.org/10.1177/0734242X16686412 | DOI Listing |
BMC Nephrol
January 2025
Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Background: IgA nephropathy (IgAN) exhibits an unpredictable trajectory, creating difficulties in prognostication, monitoring, treatment, and research planning. This study provides a comprehensive depiction of the progression of kidney function throughout the disease course, from diagnosis to a span of 36 years post-diagnosis.
Methods: We utilized a cohort of 400 Norwegian IgAN patients, from diagnosis to the occurrence of death, initiation of kidney replacement therapy (KRT), or the latest follow-up.
Knee
January 2025
Department of Anesthesiology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India. Electronic address:
Objectives: The literature does not show any studies that correlate between the morphological parameters of knee and functional outcome after anterior cruciate ligament reconstruction. The purpose of this study was to establish a correlation of morphological parameters of the knee in (magnetic resonance imaging) MRI with functional outcome in patients who underwent anterior cruciate ligament reconstruction.
Material And Methods: This was an observational study which included 63 patients who underwent anterior cruciate ligament reconstruction.
ESC Heart Fail
January 2025
Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Berlin, Germany.
Aims: Patients with heart failure with preserved ejection fraction represent half of the heart failure patients nowadays, an at least steady trend due to the aging of the population. We investigated whether the parameters obtained from cardiopulmonary exercise testing (CPET) correlated with the prognosis of these patients. This prospective observational cohort study assesses the relationship between the CPET parameters peakVO and VE/VCO slope and the number of heart failure hospitalizations or cardiovascular death of these patients.
View Article and Find Full Text PDFCrit Care
January 2025
Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, Unity Health Toronto, Toronto, ON, Canada.
Background: In patients with acute hypoxemic respiratory failure (AHRF) under mechanical ventilation, the change in pressure slope during a low-flow insufflation indicates a global airway opening pressure (AOP) needed to reopen closed airways and may be used for titration of positive end-expiratory pressure.
Objectives: To understand 1) if airways open homogeneously inside the lungs or significant regional AOP variations exist; 2) whether the pattern of the pressure slope change during low-flow insufflation can indicate the presence of regional AOP variations.
Methods: Using electrical impedance tomography, we recorded low-flow insufflation maneuvers (< 10 L/min) starting from end-expiratory positive pressure 0-5 cmHO.
J Arrhythm
February 2025
Department of Cardiovascular Medicine, Faculty of Medical Sciences University of Fukui Fukui Japan.
Background: Accurate prediction for survival in individualized patients with cardiac resynchronization therapy with a defibrillator (CRT-D) is difficult.
Methods: We analyzed the New Japan cardiac device treatment registry (JCDTR) database to develop a survival prediction model for CRT-D recipients.
Results: Four hundred and eighty-two CRT-D recipients, at the implantation year 2018-2021, with a QRS width ≥120 ms and left ventricular ejection fraction (LVEF) ≤35% at baseline, were analyzed.
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