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Community-Acquired Respiratory Virus Infections: A Threat to Long-Term survivors after Allogeneic Stem Cell Transplant?
Clin Infect Dis
December 2024
Department of Hematology. Hospital Clínico Universitario of Valencia, Spain. INCLIVA, Biomedical Research Institute, Valencia, Spain.
Background: Studies on late community-acquired respiratory virus (CARV) infections in long-term allogeneic hematopoietic stem cell transplantation (allo-HCT) survivors are scarce, creating knowledge gaps on the epidemiology, risk of progression to lower respiratory tract disease (LRTD), and conditions linked to poor outcomes.
Patients And Methods: We included consecutive CARV infection episodes occurring up to six months after allo-HCT registered in our database from December 2013 to June 2023 at two Spanish transplant centers.
Results: Among 426 allo-HCT recipients, 1070 CARV episodes were recorded, 791 (74%) with only upper respiratory tract disease (URTD) and 279 (15%) progressing to LRTD, at a median of 18.
Infective pulmonary diseases and the eye: a narrative review.
Monaldi Arch Chest Dis
September 2024
Department of Pulmonary Medicine, All India Institute of Medical Sciences, Rajkot.
Article Synopsis
- The text highlights the connection between pulmonary infections and ocular diseases, stressing the importance of understanding this relationship for effective management of both conditions.* ! -
- Ocular tuberculosis, while often lacking pulmonary symptoms, can impact various eye structures, requiring specific tests to confirm its diagnosis and presenting risks of toxic optic neuropathy from certain anti-TB medications.* ! -
- Several respiratory viruses also affect both the lungs and eyes, and there is a call for more research to improve diagnosis and identify biomarkers for early signs of drug-induced eye toxicity.* !
Duration of PCR positivity by type of respiratory virus among children using a multiplex PCR test.
J Med Virol
August 2024
Department of Pediatrics, Nara Prefecture General Medical Center, Nara, Japan.
Prolonged positive polymerase chain reaction (PCR) results, irrespective of the transmission risk, can lead to prolonged restrictions on daily activities and infection precaution interventions. Studies evaluating the duration of PCR positivity for multiple pathogens in a single patient cohort are scarce. This study aimed to evaluate and compare the durations of PCR positivity for multiple respiratory viruses among children and adolescents.
View Article and Find Full Text PDFChanges in seasonal respiratory viral infections among pediatric population around the COVID-19 pandemic; 2019-2023.
Eur J Clin Microbiol Infect Dis
August 2024
Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia.
Purpose: This study aims to describe the prevalence and the fluctuations of respiratory viral infections among the pediatric population in a tertiary care center during 2019-2023, parallel with the COVID-19 pandemic, and the specific preventative measures applied in the region during this time.
Methods: In this observational study, we extracted all respiratory virus PCR tests collected from pediatric patients (< 15 years old) between January 2019 and March 2023. Data on the positivity rate and prevalence of 18 respiratory viruses were presented over the study period.
The relationship between autophagy and respiratory viruses.
Arch Microbiol
March 2024
Department of Bacteriology and Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Respiratory viruses have caused severe global health problems and posed essential challenges to the medical community. In recent years, the role of autophagy as a critical process in cells in viral respiratory diseases has been noticed. One of the vital catabolic biological processes in the body is autophagy.
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