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Revamping field practicum: insights for future health services management professionals.
BMC Med Educ
January 2025
Department of Healthcare Services Management, School of Health, Zabol University of Medical Sciences, Zabol, Iran.
Background: The effectiveness of Health Services Management curricula relies heavily on practical experiences that reflect the evolving needs of the healthcare sector. This study focuses on revising Field Practicum 4 for undergraduate students to better prepare them for leadership roles in healthcare.
Methods: This qualitative and cross-sectional case study was conducted during the 2022-2023 academic year at Zabol University of Medical Sciences.
Human epidermal growth factor receptor 2 (HER2, also known as ERBB2) signaling promotes cell growth and differentiation, and is overexpressed in several tumor types, including breast, gastric and colorectal cancer. HER2-targeted therapies have shown clinical activity against these tumor types, resulting in regulatory approvals. However, the efficacy of HER2 therapies in tumors with HER2 mutations has not been widely investigated.
View Article and Find Full Text PDFDevelopment of Public Health Center-Based Culturally Tailored Hypertension Self-Care Intervention Among Adults in Rural Ghana.
Public Health Nurs
January 2025
Department of Medical Humanities and Social Sciences, College of Medicine, Yonsei University, Seoul, South Korea.
Objectives: Develop a primary health care-based nurse-led culturally tailored hypertension self-care intervention for rural residents.
Design: The culturally tailored hypertension self-care intervention was developed using a six-step intervention mapping approach that involved: needs assessment using literature review and interviews; setting program goals using integrated thematic synthesis method; selecting intervention modules through the process dimension of the self-care theory of chronic illness; producing program components and materials by developing intervention modules using the motivational interviewing and behavior change techniques; planning program adoption by encouraging sustainable behavior; and evaluation using the education content validity index in health and the intervention acceptability, appropriateness, and feasibility scale.
Measurements: Education content validity index in health and the intervention acceptability, appropriateness, and feasibility scale.
Definition and diagnostic criteria of clinical obesity.
Lancet Diabetes Endocrinol
January 2025
Division of Diabetes & Nutritional Sciences, School of Cardiovascular and Metabolic Medicine & Sciences, King's College London, London, UK; Catholic University of the Sacred Heart, Rome, Italy; University Polyclinic Foundation Agostino Gemelli IRCCS, Rome, Italy.
A constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer.
Cancer Cell
January 2025
Cancer Systems Biology Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Centre for Cancer Evolution, Bart's Cancer Institute, Queen Mary University London, London EC1M 6AU, UK. Electronic address:
Fewer than 50% of metastatic deficient mismatch repair (dMMR) colorectal cancer (CRC) patients respond to immune checkpoint inhibition (ICI). Identifying and expanding this patient population remains a pressing clinical need. Here, we report that an interferon-high immunophenotype locally enriched in cytotoxic lymphocytes and antigen-presenting macrophages is required for response.
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