. To investigate infection rate and evaluate a combined set of tests for diagnosis in Vietnamese patients with acute peptic ulcer bleeding (PUD). . Consecutive patients with acute PUB were enrolled prospectively. Rapid urease test (RUT) with 3 biopsies was carried out randomly. Patients without RUT or with negative RUT received urea breath test (UBT) and serological and urinary antibody tests. was considered positive if RUT or any noninvasive test was positive. Patients were divided into group A (RUT plus noninvasive tests) and group B (only noninvasive tests). . The overall infection rate was 94.2% (161/171). Groups A and B had no differences in demographic characteristics, bleeding severity, endoscopic findings, and proton pump inhibitor use. positive rate in group A was significantly higher than that in group B (98.2% versus 86.7%, = 0.004). The positive rate of RUT was similar at each biopsy site but significantly increased if RUT results from 2 or 3 sites were combined ( < 0.05). . infection rate in Vietnamese patients with acute PUB is high. RUT is an excellent test if at least 2 biopsies are taken.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241452PMC
http://dx.doi.org/10.1155/2017/3845067DOI Listing

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