There was analyzed the prevalence of transfusion-transmissible infections among blood donors and its components by examining the monitoring of donor withdrawal to donations, the absolute structure of defect in the Blood Center of Pavlodar region (BCPR) of the Republic of Kazakhstan. The results quality was ensured by the compliance of the rules and conditions of the analytical and post analytical stages of the internal quality control. It is shown that the need to improve the work of a single donor's information center (EDITS), because Only 11.6% of potential donors excluded from donation on the first-aid control stage, which increases the risk of transfusion-transmissible infections. The absolute blood defect during the study period increased in 3.9 times mainly due the transfusion-transmissible infections (47.6%), while a large share of both primary and repeated laboratory monitoring have made hepatitis B (64.1%) and C (86.5%). The share of unpaid donors (92.4%) of the total number of absolute defect is higher than paid donors (7.6%). Antibodies HCV, HBSAg, Luis 10 times more frequently detected in primary donors than repeated.

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