Undersedation is a risk factor for the development of subglottic stenosis in intubated children.

J Pediatr (Rio J)

Universidade Federal do Rio Grande do Sul (UFRGS), Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Porto Alegre, RS, Brazil; Hospital de Clínicas de Porto Alegre, Unidade de Pneumologia Pediátrica, Porto Alegre, RS, Brazil.

Published: November 2017

AI Article Synopsis

  • The study aimed to examine how sedation levels in intubated children might influence the risk of developing subglottic stenosis.
  • The research involved monitoring intubated patients aged 30 days to 5 years in a pediatric intensive care unit, using COMFORT-B scores to assess sedation, and performing laryngoscopy to check for laryngeal injuries.
  • Results showed that 11.1% of the children developed subglottic stenosis, and those affected were found to be significantly less sedated compared to those who did not experience this complication.

Article Abstract

Objective: To analyze the level of sedation in intubated children as a risk factor for the development of subglottic stenosis.

Methods: All patients between 30 days and 5 years of age who required endotracheal intubation in the pediatric intensive care unit between 2013 and 2014 were included in this prospective study. They were monitored daily and COMFORT-B scores were obtained. Flexible fiber-optic laryngoscopy was performed within eight hours of extubation, and repeated seven to ten days later if the first examination showed moderate to severe laryngeal injuries. If these lesions persisted and/or if the child developed symptoms in the follow-up period, microlaryngoscopy under general anesthesia was performed to evaluate for subglottic stenosis.

Results: The study included 36 children. Incidence of subglottic stenosis was 11.1%. Children with subglottic stenosis had a higher percentage of COMFORT-B scores between 23 and 30 (undersedated) than those who did not develop subglottic stenosis (15.8% vs. 3.65%, p=0.004).

Conclusion: Children who developed subglottic stenosis were less sedated than children who did not develop subglottic stenosis.

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Source
http://dx.doi.org/10.1016/j.jped.2016.10.006DOI Listing

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