AI Article Synopsis
- Skin cancer rates have been rising, but most sunscreens only protect against sunburn rather than providing comprehensive protection.
- Current sunscreen ingredients often have issues like low effectiveness and potential toxicity, highlighting the need for better options.
- Researchers have created new compounds with improved stability and protective qualities for sunscreens, resulting in formulations that offer superior solar protection.
Article Abstract
Skin cancer incidence has been increasing in the last decades, but most of the commercial formulations used as sunscreens are designed to protect only against solar erythema. Many of the active components present in sunscreens show critical weaknesses, such as low stability and toxicity. Thus, the development of more efficient components is an urgent health necessity and an attractive industrial target. We have rationally designed core moieties with increased photoprotective capacities and a new energy dissipation mechanism. Using these scaffolds, we have synthesized a series of compounds with tunable properties suitable for their use in sunscreens, and enhanced properties in terms of stability, light energy dissipation, and toxicity. Moreover, some representative compounds were included in final sunscreen formulations and a relevant solar protection factor boost was measured.
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| http://dx.doi.org/10.1002/anie.201611627 | DOI Listing |
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