AI Article Synopsis
- Adrenal cortical carcinomas (ACC) are rare and aggressive cancers with an incidence rate of 1-2 cases per million, constituting 0.05-0.2% of all cancers.
- Approximately 60% of ACC cases are functional tumors, with 40% leading to Cushing's syndrome, while a small percentage (2.5-11%) present with hypertension due to excess aldosterone secretion, typically as unilateral tumors.
- This text presents a unique case of bilateral aldosterone-producing adrenocortical carcinoma (APAC) in a 22-year-old male, which has not been reported before.
Article Abstract
Adrenal cortical carcinomas (ACC) are rare aggressive malignant neoplasms with a reported incidence of 1-2 cases per 1 million population and account for 0.05-0.2 % of all malignancies. About 60 % are functional tumors and majority, 40 % present with Cushing's syndrome. Rarely, 2.5 to 11 % present with hypertension due to increased secretion of aldosterone and are usually unilateral. Bilateral aldosterone-producing adrenocortical carcinoma (APAC) has not been reported yet. We report a case of bilateral APAC in a 22-year-old male.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236019 | PMC |
| http://dx.doi.org/10.1007/s13193-016-0563-8 | DOI Listing |
Publication Analysis
Top Keywords
bilateral aldosterone-producing
8
aldosterone-producing adrenocortical
8
adrenocortical carcinoma
8
carcinoma rare
4
rare entity
4
entity adrenal
4
adrenal cortical
4
cortical carcinomas
4
carcinomas acc
4
acc rare
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!