The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, including 1 case of pneumonic plague.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382724PMC
http://dx.doi.org/10.3201/eid2303.161212DOI Listing

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