Objective: To evaluate low-pressure bone stenting combined with cementoplasty in extensive lytic lesions.
Methods: A single-centre study involving four consecutive patients (four women) with extensive lytic tumours was performed. The average age was 65 years. Surgical treatment was not indicated or not wished for by the patients. Institutional review board approval and informed consent were obtained. Percutaneous consolidation was performed by an interventional radiologist under fluoroscopy guidance. Follow-up was assessed using the visual analogue scale (VAS).
Results: Under general (n = 2) or local (n = 2) anaesthesia, five 11-gauge bone biopsy needles were advanced in four lesions. Five auto-expandable uncovered stents (10-14 mm diameter and 40-60 mm long) were inserted. In all cases, bone cement was successfully placed into the tumours. The volume of cement that was injected through the cannulas into the stents was 5-10 mL. Using VAS, pain decreased from more than 9/10 preoperatively to less than 2/10 after the procedure for all patients (p < 0.05). No complications occurred during the follow-up (8-19 months).
Conclusion: This study suggests that cementoplasty combined with low-pressure bone stenting could allow effective bone stabilization resulting in pain relief.
Key Points: • Low-pressure bone stenting is possible. • This technique improves cement injection control. • The procedure allows effective bone stabilization resulting in pain relief.
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http://dx.doi.org/10.1007/s00330-016-4703-x | DOI Listing |
Arch Virol
January 2025
Jiangsu Province Engineering Research Center for Marine Bio-resources Sustainable Utilization, College of Oceanography, Hohai University, Nanjing, Jiangsu, China.
In this study, a lytic phage, named PG216, was obtained from seawater collected in Qingdao, using Vibrio parahaemolyticus strain G299 as its host. Transmission electron microscopy revealed that phage PG216 has an icosahedral head with a diameter of 100 ± 6.7 nm and a contractible tail with a length of 126 ± 6.
View Article and Find Full Text PDFCureus
December 2024
General Surgery, P.E.S. Institute of Medical Sciences and Research, Kuppam, IND.
This case presents a rare and aggressive manifestation of malignant melanoma, initially presenting as a chest wall swelling in a young male with a history of trauma and subsequent management for hemothorax and pyothorax. The complexity of this case lies in its atypical presentation and the challenges posed in diagnosis and treatment. A 30-year-old gentleman presented to the general surgery clinic with a chief complaint of swelling on the right side of his chest, persisting for two months following a traumatic fall, which later resulted in hemothorax and prothorax required drainage and eventually ended up developing a swelling requiring further investigations.
View Article and Find Full Text PDFJ Neurosurg Case Lessons
December 2024
Department of Neurosurgery, University of Mississippi Medical Center, Jackson, Mississippi.
Background: The authors describe the case of a 35-year-old male who presented with back pain and painful masses on his upper extremities. He had a known sacral lesion identified 1 year prior at an outside facility, suspected to be coccidioidomycosis on biopsy, but the workup was not completed because the patient left against medical advice and was lost to follow-up. Computed tomography (CT) and magnetic resonance imaging revealed lytic destructive lesions involving the calvaria, thoracolumbar spine, and sacrum, concerning for an active and disseminated infection.
View Article and Find Full Text PDFbioRxiv
December 2024
Department of Medical Biology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
Caviid gammaherpesvirus 1 (CaGHV-1), formerly known as the guinea pig herpes-like virus, is an oncogenic gammaherpesvirus with a sequenced genome but an as-yet uncharacterized transcriptome. Using nanopore long-read RNA sequencing, we annotated the CaGHV-1 genome and constructed a detailed transcriptomic atlas. Our findings reveal diverse viral mRNAs and non-coding RNAs, along with mapped promoter elements for each viral gene.
View Article and Find Full Text PDFInt J Surg Case Rep
November 2024
Hôpital Régional de Ziguinchor, Senegal.
Introduction And Importance: Giant cell tumor is a benign primary bone tumor of mesenchymal origin that mainly affects the long bones. Involvement of the bones of the foot is rare with an incidence of 1 to 2 %. We report a case of giant cell tumor of the talus in a 36-year-old man.
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