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http://dx.doi.org/10.1177/112070000201200208 | DOI Listing |
Iowa Orthop J
January 2025
Rothman Orthopaedic Institute, Philadelphia, Pennsylvania, USA.
Background: Dislocation remains a common complication following total hip arthroplasty (THA). Previous literature has shown that the femoral head-to-neck ratio is essential in hip motion, function, and stability. While large femoral heads and dual mobility bearings have been developed to improve stability, it remains unknown if the ratio between femoral head size to acetabular cup size also plays a role in stability.
View Article and Find Full Text PDFBiomed Rep
March 2025
Circulating Biomarkers Laboratory, Pathology Department, Faculty of Medical Sciences, Rio de Janeiro State University, Rio de Janeiro 20550-170, Brazil.
Osteosarcoma (OS) is the most common malignant bone tumor affecting adolescents and young adults and it usually occurs in the long bones of the extremities. The detection of cancer-related genetic alterations has a growing effect in guiding diagnosis, prognosis and targeted therapies. However, little is known about the molecular aspects involved in the etiology and progression of OS, which limits options for targeted therapies.
View Article and Find Full Text PDFBMC Endocr Disord
January 2025
The First School of Clinical Medicine, Lanzhou University, No.199 Donggang West Road, Chengguan District, Lanzhou, Gansu Province, 730000, China.
Background: Thyroid hormone plays an important role in accumulating bone development and regulating bone metabolism. It is established that hypothyroidism is linked to increased risk of osteoporosis and fracture. However, the effects of levothyroxine (LT4) treatment on bone for hypothyroid patients remain controversial.
View Article and Find Full Text PDFMed Biol Eng Comput
January 2025
Department of Pediatric Orthopedics, Xinhua Hospital Affiliated With Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Proximal femoral fractures in children are challenging in clinical treatment due to their unique anatomical and biomechanical characteristics. The distribution and characteristics of fracture lines directly affect the selection of treatment options and prognosis. Pediatric proximal femur fractures exhibit distinctive features, with the distribution and characteristics of the fracture line playing a crucial role in deciding optimal treatment.
View Article and Find Full Text PDFJ Exp Orthop
January 2025
Department of Orthopaedic Surgery and Trauma University Center of Montpellier, University of Montpellier Montpellier France.
Purpose: Gap-balanced total knee arthroplasty (TKA) technique relies on initial ligament evaluation, particularly in patient-specific implantation using computer-assisted technologies. This cadaveric study aimed to compare the reproducibility and reliability of medial and lateral gap measurements between manual stress testing and dynamic ligament balancer.
Methods: Initial gap acquisitions were assessed from eight cadaveric knees (four specimens) during the same navigated TKA procedure by five differently skilled surgeons (three seniors and two juniors).
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