Yeast Vps13 is a member of a conserved protein family that includes human homologues associated with neurodegenerative and developmental disorders. In this issue, De et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201606078) establish direct roles for Vps13 and its surprising binding partner, the calcium-binding centrin Cdc31, in trans-Golgi network (TGN) to endosome traffic and TGN homotypic fusion.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294792 | PMC |
| http://dx.doi.org/10.1083/jcb.201612026 | DOI Listing |
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