The clinical significance of minor esophageal motility disorders is unclear, though they typically carry a benign course. Distal esophageal spasm progressing to achalasia has been reported, although it appears to be rare. We report a case of a patient with dysphagia and chest pain who was found to have ineffective esophageal motility on high-resolution manometry, which developed into distal esophageal spasm and then progressed to type III achalasia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226198PMC
http://dx.doi.org/10.14309/crj.2016.156DOI Listing

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