In the present study, vitamin D status and its associations with rheumatoid arthritis in Korean women were investigated. Total 2,162 women's data from the Korea National Health and Nutrition Examination Survey during 2008-2014 ware analyzed by complex sampling design logistic regression analysis and complex sampling design general linear model. Women who over 19 years old were included, and who has osteoporosis or abnormal parathyroid hormone or renal failure or liver cirrhosis or abnormal creatinine were excluded. Age and body mass index were used as covariate. In the present study, we have shown that vitamin D status were not associated with development of rheumatoid arthritis in Korean women as well were not associated with pain and quality of life in Korean women with rheumatoid arthritis. Based on the present study and considering the effects of vitamin D on fracture and osteoporosis, it can be suggested that additional cohort study and cost-effectiveness analysis are needed.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227325 | PMC |
http://dx.doi.org/10.12965/jer.1632870.435 | DOI Listing |
Int J Med Sci
January 2025
Reproductive Medicine Center, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
While the gluten-free diet (GFD) is primarily used to treat celiac disease (CD), recent research suggests it may also offer benefits for autoimmune-related diseases (ARDs), though findings remain inconsistent. This study aimed to investigate the potential protective effect of a GFD against ARDs by Mendelian Randomization (MR) analysis. Utilizing data from over 500,000 samples from the UK Biobank and other publicly available genome-wide association studies (GWAS), MR analysis revealed a significant negative causal relationship between GFD and the risk of developing rheumatoid arthritis (RA) (OR = 0.
View Article and Find Full Text PDFCureus
December 2024
Orthopaedic Surgery, National Hospital Organization, Osaka Minami Medical Center, Kawachinagano, JPN.
Background: According to the conventional postoperative procedure after total ankle arthroplasty (TAA) for end-stage osteoarthritis (OA) and rheumatoid arthritis (RA), mobilization and weight-bearing are currently started after completion of wound healing. Recently, an early rehabilitation program after cemented TAA with a modified anterolateral approach has been attempted because this approach could provide stable wound healing. To investigate the possibility of expediting rehabilitation, this study evaluated the feasibility, safety, and universality of an early rehabilitation program after cemented TAA using a modified anterolateral approach, even when a surgeon was completely changed.
View Article and Find Full Text PDFMod Rheumatol
December 2024
Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 4668560, Japan.
Objectives: To identify factors associated with probable sarcopenia in patients with rheumatoid arthritis (RA).
Methods: Probable sarcopenia was diagnosed using the SARC-F questionnaire. Patients with difficult-to-treat RA (D2T-RA) were defined as those with a history of using ≥2 biological/targeted synthetic (b/ts) disease-modifying antirheumatic drugs (b/tsDMARDs) who had moderate or high disease activity.
Mod Rheumatol
December 2024
Department of General Practice N2, South Kazakhstan Medical Academy, Shymkent, Kazakhstan.
Adv Rheumatol
January 2025
Department of Ophthalmology, Otolaryngology, Head and Neck Surgery, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Background: Endoplasmic reticulum stress (ERS) and the unfolded protein response (UPR) are adaptive mechanisms for conditions of high protein demand, marked by an accumulation of misfolded proteins in the endoplasmic reticulum (ER). Rheumatic autoimmune diseases (RAD) are known to be associated with chronic inflammation and an ERS state. However, the activation of UPR signaling pathways is not completely understood in Sjögren's disease (SD).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!