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Genomic Distance with High Indel Costs. | LitMetric

We determine complexity of computing the DCJ-indel distance, when DCJ and indel operations have distinct constant costs, by showing an exact formula that can be computed in linear time for any choice of (constant) costs for DCJ and indel operations. We additionally consider the problem of triangular inequality disruption and propose an algorithmically efficient correction on each member of the family of DCJ-indel.

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http://dx.doi.org/10.1109/TCBB.2016.2555301DOI Listing

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