AI Article Synopsis

  • Eight children experienced contact burns and blisters after using sennosides for severe constipation, likely due to prolonged exposure while in diapers.
  • The injuries were noted to happen overnight, highlighting the risk of using these laxatives without proper timing.
  • To prevent these side effects, it is recommended to administer sennosides during the day, allowing for bowel movements to occur when the children are awake.

Article Abstract

Eight children treated for severe constipation with sennosides unexpectedly developed contact burns with blisters secondary to the use of these laxatives. All patients wore diapers, and the injuries occurred overnight. To avoid this side effect, we recommend that patients treated with sennosides, especially those in diapers, receive the medication at a time that allows for bowel movements to occur during the day and not overnight.

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Source
http://dx.doi.org/10.1111/pde.13068DOI Listing

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