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Four-dimensional computed tomography analysis of bicuspid aortic valves.
JTCVS Tech
October 2024
Department of Cardiothoracic Surgery, Limoges University Hospital, Limoges, France.
Article Synopsis
- The study aimed to assess how 4D analysis using multiphase cardiac CT can help describe the aortic annulus in patients with bicuspid aortic valves, comparing it to those with normal tricuspid valves.
- The methodology involved analyzing cardiac CT scans of 15 BAV patients and 15 TAV patients, measuring various 3D characteristics of the aortic annulus across different phases of the heart's cycle.
- Results showed that the aortic annulus in BAV patients was significantly larger in multiple dimensions compared to TAV patients and demonstrated that 3D shape analysis can effectively differentiate between various types of BAV, revealing important anatomical details like the position of nonfunctional commissures.
Lake shape and the characteristics of migration behavior modify Atlantic salmon smolt migration success through lakes.
J Fish Biol
October 2024
Scottish Centre for Ecology and the Natural Environment, School of Biodiversity One Health and Veterinary Medicine, University of Glasgow, Glasgow, UK.
Migration is a high-risk behavior. For the Atlantic salmon, Salmo salar, migrating from its river nursery area to marine feeding grounds, the magnitude of risk varies with habitat type. Passage through lakes, in particular, is associated with low rates of migration success.
View Article and Find Full Text PDFDynamic behavior of DNA molecules in microchannels: exploring deflective, elliptical, and spin motions induced by Saffman and Magnus forces.
Lab Chip
July 2024
Key Laboratory of Photoelectric Technology of Shaanxi Province, National Center for International Research of Photoelectric Technology & Nano-Functional Materials and Application, Institute of Photonics and Photon-Technology, Northwest University, Xi'an 710069, China.
Precise manipulation of individual DNA molecules entering and leaving the channel ports, as well as their smooth passage across the channel, is essential for the detection and screening of DNA molecules using nano-/micro-fluidic technologies. In this paper, by combining single-molecule fluorescence imaging and numerical simulations, the motion states of DNA molecules translocating through a microfluidic channel under the action of the applied electric field are monitored and analyzed in detail. It is found that, under certain conditions of the applied electric field DNA molecules exhibit various motion states, including translation crossing, deflection outflow, reverse outflow, reciprocal movement, and elliptical movement.
View Article and Find Full Text PDFBicuspid valve CT registry of balloon-expandable TAVR: BETTER TAVR registry.
Catheter Cardiovasc Interv
July 2024
McMaster University and Hamilton Health Sciences, Hamilton, Canada.
Background: The anatomic substrate of bicuspid valves may lead to suboptimal TAVR stent expansion and geometry.
Aim: We evaluated determinants of stent geometry in bicuspid valves treated with Sapien transcatheter aortic valve replacement (TAVR) valves.
Methods: A multicenter retrospective registry of patients (February 2019 to August 2022) who underwent post-TAVR computed tomography to determine stent area (vs.
Impact of stroke volume assessment by three-dimensional transesophageal echocardiography on the classification of low-gradient aortic stenosis.
J Echocardiogr
September 2024
Cedars-Sinai Medical Center, Smidt Heart Institute, Beverly Blvd, Los Angeles, CA, 8700, USA.
Article Synopsis
- Accurate assessment of flow status is vital for patients with low-gradient aortic stenosis (AS), but the role of 3D transesophageal echocardiography (3DTEE) in this assessment is not fully understood.
- The study involved reviewing patients from 2019 to 2022, categorizing them into low-flow/low-gradient (LF-LG) and normal-flow/low-gradient (NF-LG) groups based on echocardiography, and analyzing differences in left ventricular outflow tract (LVOT) geometry.
- Results showed that LF-LG patients had a significantly higher LVOT ellipticity index, indicating a greater mismatch in flow status classification compared to NF-LG patients; thus, 3DTEE-derived
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