We present a new approach of integrated maximum current density (IMCD) for the noninvasive detection of myocardial infarction (MI) using magnetocardiography (MCG) data acquired from a superconducting quantum interference device (SQUID) system. In this paper, we investigated the relationship of the maximum current density (MCD) in the current density map and the underlying equivalent current dipole (ECD) based on a novel method of reconstructing the ECD in the extremum circle of the magnetic field map. The performance of IMCD and the integrated ECD (IECD) approaches were also evaluated by using 61-channel MCG data from 39 healthy subjects and 102 patients with ST elevation myocardial infarction (STEMI). Statistical analysis of the healthy and STEMI groups demonstrate that the IMCD approach obtains sensitivity and specificity up to 91.2% and 84.6%, somewhat higher than that of IECD, respectively. The results indicate that IMCD provides spatiotemporal information regarding cardiac electrical activity during ventricular repolarization. This approach may be helpful to diagnose MI in clinic application. The physical concept of the approach is also explained in this paper.
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http://dx.doi.org/10.1109/JBHI.2017.2649570 | DOI Listing |
Sci Rep
January 2025
Department of Applied Animal Science and Welfare, Swedish University of Agricultural Sciences, Gothenburg, Sweden.
Zebrafish are widely used in research, accounting for approximately 50% of all laboratory fish across Europe. Due to their rapid reproduction and aging, effective and practical euthanasia methods are necessary for managing large stocks. This study investigated whether adult zebrafish can be euthanised by delivering an electrical current directly via the water in their housing aquaria.
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January 2025
College of Earth Science and Engineering, Shandong University of Science and Technology, Qingdao, Shandong Province, China.
The unsaturated hydraulic conductivity (K) is one of the most important properties for evaluating moisture and gas migration in soil. However, the precise measurement of K in the laboratory often requires considerable time and economic costs. Currently, the most commonly used method to calculate K is to obtain it from the soil-water characteristic curve (SWCC) and saturated hydraulic conductivity.
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January 2025
The PRIDE Study/PRIDEnet, Stanford University School of Medicine, Stanford, CA, USA.
Structural stigma towards gender minority (GM; people whose current gender does not align with sex assigned at birth) people is an important contributor to minority stress (i.e., stress experienced due to one's marginalized GM identity), although existing variables are unclear in their inclusion of social norms, or societal stigma, as a key component of the construct.
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January 2025
Electrical and Computer Engineering Department, University of Memphis, Memphis, TN, 38152, USA.
Oral squamous cell carcinoma (OSCC) is the most common form of oral cancer, with increasing global incidence and have poor prognosis. Tumour-infiltrating lymphocytes (TILs) are recognized as a key prognostic indicator and play a vital role in OSCC grading. However, current methods for TILs quantification are based on subjective visual assessments, leading to inter-observer variability and inconsistent diagnostic reproducibility.
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January 2025
Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of California San Diego School of Medicine, La Jolla, California, USA
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease, is the most common cause of chronic liver disease in children. MASLD encompasses a spectrum of liver disease and can be severe, with 10% of affected children presenting with advanced fibrosis. While biopsy remains the most accurate method for diagnosing and staging the disease, MRI proton density fat fraction and magnetic resonance elastography are the most reliable non-invasive measures for assessing steatosis and fibrosis, respectively.
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