The automatic triggering of a critical incident review for all unexpected cardiac arrests, as proposed by the National Patient Safety Agency (news August 25), should enable organisations to identify readily the remedial factors that may contribute towards a 'failure to rescue'.
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http://dx.doi.org/10.7748/ns.24.52.33.s45 | DOI Listing |
Pharmaceuticals (Basel)
January 2025
Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka 72388, Saudi Arabia.
Fructose-driven metabolic disorders, such as obesity, non-alcoholic fatty liver disease (NAFLD), dyslipidemia, and type 2 diabetes, are significant global health challenges. Ketohexokinase C (KHK-C), a key enzyme in fructose metabolism, is a promising therapeutic target. α-Mangostin, a naturally occurring prenylated xanthone, has been identified as an effective KHK-C inhibitor, prompting exploration of its analogs for enhanced efficacy.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Intelligent Control Laboratory, Xi'an Research Institute of High Technology, Xi'an 710025, China.
For public security purposes, distributed surveillance systems are widely deployed in key areas. These systems comprise visual sensors, edge computing boxes, and cloud servers. Resource scheduling algorithms are critical to ensure such systems' robustness and efficiency.
View Article and Find Full Text PDFSensors (Basel)
January 2025
College of Energy and Power Engineering, Xihua University, Chengdu 610039, China.
Artificial intelligence (AI) technologies have been widely applied to the automated detection of pipeline leaks. However, traditional AI methods still face significant challenges in effectively detecting the complete leak process. Furthermore, the deployment cost of such models has increased substantially due to the use of GPU-trained neural networks in recent years.
View Article and Find Full Text PDFMolecules
January 2025
Key Laboratory of Forest Plant Ecology of Ministry of Education, Northeast Forestry University, Hexing Road 26, Harbin 150040, China.
(ASC) contains a variety of bioactive compounds and serves as an important traditional Chinese medicinal resource. However, its prolonged growth cycle and reliance on wild populations limit its practical use. To explore the potential of (ASF) as an alternative, this study focused on optimizing the extraction process and assessing the bioactivity of stem extracts.
View Article and Find Full Text PDFMicroorganisms
January 2025
Institute of Aquaculture Torre de la Sal (IATS-CSIC), 12595 Ribera de Cabanes, Spain.
The significant microbiota variability represents a key feature that makes the full comprehension of the functional interaction between microbiota and the host an ongoing challenge. To overcome this limitation, in this study, fish intestinal microbiota was analyzed through a meta-analysis, identifying the core microbiota and constructing stochastic Bayesian network (BN) models with SAMBA. We combined three experiments performed with gilthead sea bream juveniles of the same hatchery batch, reared at the same season/location, and fed with diets enriched on processed animal proteins (PAP) and other alternative ingredients (NOPAP-PP, NOPAP-SCP).
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