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Comparative digestive biology between the ponyfishes from the Pranburi River estuary, Thailand.
J Fish Biol
April 2024
Department of Marine Science, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
We investigated the digestive biology of two prevalent leiognathid species in Pranburi River estuary, Thailand: the decorated ponyfish (Nuchequula gerreoides) and the splendid polyfish (Eubleekeria splendens). A total of 632 samples collected from February to April and September to November 2017 were analysed using morphological and histological approaches. The overall structures were similar between the species: a short mucous-cell-rich oesophagus region, a well-developed gastric gland uniformly present across the stomach's mucosal layer, and three finger-like pyloric caeca between the stomach and intestine.
View Article and Find Full Text PDFMesoporous covalent organic framework microspheres with dual-phase separation strategy for high-purity glycopeptide enrichment.
J Chromatogr A
November 2022
National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, PR China. Electronic address:
High-performance porous materials and rational enrichment strategies are crucial during sample pretreatment process in glycoproteomics analysis. Herein, we report a dual-phase separation strategy based on hydrophobic and hydrophilic mesoporous covalent-organic framework (COF) microspheres for high-purity glycopeptide enrichment for the first time. The COF microspheres (about 1.
View Article and Find Full Text PDFAuNPs/CdS QDs/CeO ternary nanocomposite coupled with scrollable three-dimensional DNA walker mediated cycling amplification for sensitive photoelectrochemical miRNA assay.
Anal Chim Acta
October 2022
Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China. Electronic address:
Herein, a novel ternary nanocomposite (AuNPs/CdS QDs/CeO) with excellent photoelectrochemical (PEC) performance was synthesized as signal probe to construct a near-zero background biosensor for sensitive miRNA-182-5p detection, by integrating with a scrollable three-dimensional (3D) DNA walker mediated cleavage cycling amplification. Impressively, the formation and rolling of scrollable 3D DNA walker triggered by target could realize dynamic, rapid and specific digestion of hairpin DNA on electrode with the aid of Exonuclease III (Exo III), which thus exposed abundant binding sites for assembling stable DNA labeled AuNPs/CdS QDs/CeO nanoprobes. Thanks to the formation of type-II heterojunction (between CeO and CdS QDs) and Schottky junction (generated by CeO and AuNPs), an ideal photoelectric conversion efficiency accompanied with stunningly improved photocurrent was thus acquired for significantly improving the detection sensitivity.
View Article and Find Full Text PDFApplication of artificial intelligence in a real-world research for predicting the risk of liver metastasis in T1 colorectal cancer.
Cancer Cell Int
January 2022
Division of Digestive Surgery, Xijing Hospital of Digestive Diseases, Airforce Medical University, Xi'an, China.
Background: Liver is the most common metastatic site of colorectal cancer (CRC) and liver metastasis (LM) determines subsequent treatment as well as prognosis of patients, especially in T1 patients. T1 CRC patients with LM are recommended to adopt surgery and systematic treatments rather than endoscopic therapy alone. Nevertheless, there is still no effective model to predict the risk of LM in T1 CRC patients.
View Article and Find Full Text PDFEntropy-driven electrochemiluminescence ultra-sensitive detection strategy of NF-κB p50 as the regulator of cytokine storm.
Biosens Bioelectron
March 2021
NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, 214063, China; Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China. Electronic address:
2019 novel coronavirus (2019-nCoV) with strong contagion in the crowd, has ravaged worldwide and severely impacts the human health and epidemic prevention system, by producing a series of significant stress reactions in the body to induce further cytokine storm. Transcription factors (TFs) served as essential DNA binding proteins play an integral role in regulating cytokine storm, and the detection of it in the human coronavirus environment provides especially valuable approaches to diagnosis and treatment of 2019-nCoV and development of antiviral drugs. In this work, an entropy-driven electrochemiluminescence (ECL) biosensor was constructed for ultra-sensitive bioassay of NF-κB p50.
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