Background And Objectives: Ultrasound-guided regional anesthesia facilitates an approach to sensitive targets such as nerve clusters without contact or inadvertent puncture. We compared accuracy of needle placement with a novel passive magnetic ultrasound needle guidance technology (NGT) versus conventional ultrasound (CU) with echogenic needles.
Methods: Sixteen anesthesiologists and 19 residents performed a series of 16 needle insertion tasks each, 8 using NGT (n = 280) and 8 using CU (n = 280), in high-fidelity porcine phantoms. Tasks were stratified based on aiming to contact (target-contact) or place in close proximity with (target-proximity) targets, needle gauge (no. 18/no. 22), and in-plane (IP) or out-of-plane (OOP) approach. Distance to the target, task completion by aim, number of passes, and number of tasks completed on the first pass were reported.
Results: Needle guidance technology significantly improved distance, task completion, number of passes, and completion on the first pass compared with CU for both IP and OOP approaches (P ≤ 0.001). Average NGT distance to target was lower by 57.1% overall (n = 560, 1.5 ± 2.4 vs 3.5 ± 3.7 mm), 38.5% IP (n = 140, 1.6 ± 2.6 vs 2.6 ± 2.8 mm), and 68.2% OOP (n = 140, 1.4 ± 2.2 vs 4.4 ± 4.3 mm) (all P ≤ 0.01). Subgroup analyses revealed accuracy gains were largest among target-proximity tasks performed by residents and for OOP approaches. Needle guidance technology improved first-pass completion from 214 (76.4%) per 280 to 249 (88.9%) per 280, a significant improvement of 16.4% (P = 0.001).
Conclusions: Passive magnetic NGT can improve accuracy of needle procedures, particularly among OOP procedures requiring close approach to sensitive targets, such as nerve blocks in anesthesiology practice.
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http://dx.doi.org/10.1097/AAP.0000000000000549 | DOI Listing |
A passive temperature-compensated magnetic field sensor based on the material thermal-optics effect has been proposed. The proposed structure is easy to fabricate, consisting of only two single-mode optical fibers adhered to a magnetostrictive rod and the Fabry-Perot (FP) cavity filled with polydimethylsiloxane (PDMS). Benefitting from the negative thermal-optics coefficient of PDMS, the temperature cross-sensitivity of the sensor decreased from 351.
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June 2025
Department of Radiology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, 1678 Dong Fang Road, Shanghai 200127, PR China.
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Materials (Basel)
January 2025
School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China.
Depending on high permeability, high Curie temperature, and low eddy current loss noise, nanocrystalline alloys, as the innermost layer, exhibit great potential in the construction of cylindrical magnetic shielding systems with a high shielding coefficient and low magnetic noise. This study compares a magnetic noise of 1 Hz, simulated by the finite element method (FEM), of a cylindrical nanocrystalline magnetic shield with different structural parameters based on the measured initial permeability of commercial Fe-based nanocrystalline (1K107). The simulated results demonstrate that the magnetic noise is irrelevant to the pump and probe hole diameter.
View Article and Find Full Text PDFBiosensors (Basel)
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School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Microbial contamination is an important factor threatening the safety of Chinese medicine preparations, and microfluidic detection methods have demonstrated excellent advantages in the application of rapid bacterial detection. In our study, a novel optical biosensor was developed for the rapid and sensitive detection of in traditional Chinese medicine on a microfluidic chip. Immune gold@platinum nanocatalysts (Au@PtNCs) were utilized for specific bacterial labeling, while magnetic nano-beads (MNBs) with a novel high-gradient magnetic field were employed for the specific capture of bacteria.
View Article and Find Full Text PDFDrug Deliv Transl Res
January 2025
Dr. Hari Singh Gour Central University, Sagar, 470003, MP, India.
Cancer treatments such as surgery and chemotherapy have several limitations, including ineffectiveness against large or persistent tumors, high relapse rates, drug toxicity, and non-specificity of therapy. Researchers are exploring advanced strategies for treating this life-threatening disease to address these challenges. One promising approach is targeted drug delivery using prodrugs or surface modification with receptor-specific moieties for active or passive targeting.
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