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| http://dx.doi.org/10.6061/clinics/2016(12)01 | DOI Listing |
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Promoting Health Equity, Diversity, and Inclusion in Medical and Scientific Writing and Publishing of Research: A Statement from the Inaugural Diversity, Equity, and Inclusion (DEI) Advocacy Team of the Journal of General Internal Medicine.
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Department of Medicine and Population Health, Institute for Excellence in Health Equity, New York University Grossman School of Medicine, New York, NY, USA.
The Journal of General Internal Medicine (JGIM) has a long-standing history of publishing manuscripts focused on health equity and is committed to diversity, equity, and inclusion (DEI) in scientific writing and publishing. This is extremely important in the current climate where false narratives and attacks on DEI and health equity are rampant. To demonstrate their commitment to DEI and health equity, the JGIM Editors-in-Chief created an inaugural DEI Advocacy Team.
View Article and Find Full Text PDFState-dependent neurovascular modulation induced by transcranial ultrasound stimulation.
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School of Biomedical Engineering, Shanghai Jiao Tong University, No.1954 Huashan Road, Shanghai, 200030, Shanghai, China.
Previous studies reported baseline state-dependent effects on neural and hemodynamic responses to transcranial ultrasound stimulation. However, due to neurovascular coupling, neither neural nor hemodynamic baseline alone can fully explain the ultrasound-induced responses. In this study, using a general linear model, we aimed to investigate the roles of both neural and hemodynamic baseline status as well as their interactions in ultrasound-induced responses.
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Center for Advanced Laser Technologies (CETAL), National Institute for Lasers, Plasma and Radiation Physics, Magurele-Ilfov, 077125, Romania.
Nature offers unique examples that help humans produce artificial systems which mimic specific functions of living organisms and provide solutions to complex technical problems of the modern world. For example, the development of 3D micro-nanostructures that mimic nocturnal insect eyes (optimized for night vision), emerges as promising technology for detection in IR spectral region. Here, we report a proof of principle concerning the design and laser 3D printing of all ultrastructural details of nocturnal moth Grapholita Funebrana eyes, for potential use as microlens arrays for IR detection systems.
View Article and Find Full Text PDFStromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma.
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Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Dissecting the spatial heterogeneity of cancer-associated fibroblasts (CAFs) is vital for understanding tumor biology and therapeutic design. By combining pathological image analysis with spatial proteomics, we revealed two stromal archetypes in hepatocellular carcinoma (HCC) with different biological functions and extracellular matrix compositions. Using paired single-cell RNA and epigenomic sequencing with Stereo-seq, we revealed two fibroblast subsets CAF-FAP and CAF-C7, whose spatial enrichment strongly correlated with the two stromal archetypes and opposing patient prognosis.
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