Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225876PMC
http://dx.doi.org/10.1590/0102-6720201600040020DOI Listing

Publication Analysis

Top Keywords

synchronous anal
4
anal melanoma
4
melanoma colon
4
colon adenocarcinoma
4
adenocarcinoma case
4
case report
4
report review
4
review diagnosis
4
diagnosis management
4
synchronous
1

Similar Publications

Human papillomavirus (HPV) underpins approximately 90% of squamous cell carcinomas (SCC) of the anus and perianal region. These tumors usually arise in association with precursor lesions such anal intraepithelial neoplasia/ high-grade squamous intraepithelial lesion (AIN 3/ HSIL), whereas a small subset of HPV-negative cancers may harbor mutations in TP53. Recently, vulvar lesions termed differentiated exophytic vulvar intraepithelial lesion/vulvar acanthosis with altered differentiated (DEVIL/VAAD) have been recognized as HPV-independent, TP53 wild-type precursors for vulvar carcinoma; however, analogous anal lesions have not been described.

View Article and Find Full Text PDF

The recent advances in neuroimaging technology allow us to understand how the human brain is wired in vivo and how functional activity is synchronized across multiple regions. Growing evidence shows that the complexity of the functional connectivity is far beyond the widely used mono-layer network. Indeed, the hierarchical processing information among distinct brain regions and across multiple channels requires using a more advanced multilayer model to understand the synchronization across the brain that underlies functional brain networks.

View Article and Find Full Text PDF

Intrinsic dual-emitting Si dots for high-precision and broad-range pH detection.

Anal Chim Acta

February 2025

Shenzhen Key Laboratory of Synthetic Genomics, Guangdong Provincial Key Laboratory of Synthetic Genomics, CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. Electronic address:

Background: High-precision and broad-range pH detection is critical for health status assessment, such as signal transduction, enzyme activity, endocytosis, and cell proliferation and apoptosis. Although pH-responsive ratiometric fluorescent probes offer an effective pH monitoring strategy, their preparation often requires multi-step modification and decreases fluorescence efficiency and stability. Herein, we developed a simple method to prepare fluorescent Si dots with dual emission centers for high-precision and broad-range pH monitoring, and the detection of urease based on pH-responsive Si dots and pH monitoring in living cell was further explored.

View Article and Find Full Text PDF

Combination of plasma acoustic emission signal and laser-induced breakdown spectroscopy for accurate classification of steel.

Anal Chim Acta

January 2025

Key Laboratory of High Performance Manufacturing for Aero Engine (MIIT), Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, China. Electronic address:

Background: Fast and accurate classification of steel can effectively improve industrial production efficiency. In recent years, the use of laser-induced breakdown spectroscopy (LIBS) in conjunction with other techniques for material classification has been developing. Plasma Acoustic Emission Signal (PAES) is a type of modal information separate from spectra that is detected using LIBS, and it can reflect some of the sample's physicochemical information.

View Article and Find Full Text PDF
Article Synopsis
  • - The study measures rate coefficients for reactions involving hydrated protons and various sample vapors to produce protonated monomers and dimers using ion mobility spectrometry with a tandem drift tube.
  • - The method involves analyzing ions through two drift regions, adjusting for drift times, and fitting curves to derive accurate rate coefficients for specific compounds like triethyl phosphate and phenylacetate.
  • - The proposed technique shows a relative error of 10% and is applicable to a range of substances, indicating it can reliably determine rate coefficients for reactions that form these types of protonated species.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!