Resistance diagnosis and the changing economics of antibiotic discovery.

Ann N Y Acad Sci

Fuqua School of Business and Economics Department, Duke University, Durham, North Carolina.

Published: January 2017

AI Article Synopsis

  • Point-of-care diagnostics that identify antibiotic sensitivity can boost the profitability of newly patented antibiotics, even if fewer antibiotics are sold.
  • Improvements in rapid resistance diagnostics are expected to encourage the discovery and development of new antibiotics, particularly those with a narrow range of effectiveness.
  • This advancement could help address the challenge of antibiotic resistance by promoting the use of targeted treatments instead of broad-spectrum antibiotics.

Article Abstract

Point-of-care diagnostics that can determine an infection's antibiotic sensitivity increase the profitability of new antibiotics that enjoy patent protection, even when such diagnostics reduce the quantity of antibiotics sold. Advances in the science and technology underpinning rapid resistance diagnostics can therefore be expected to spur efforts to discover and develop new antibiotics, especially those with a narrow spectrum of activity that would otherwise fail to find a market.

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Source
http://dx.doi.org/10.1111/nyas.13303DOI Listing

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