Introduction: Hospital-based medical services are increasingly utilizing team-based pagers and smartphones to streamline communications. However, an unintended consequence may be higher volumes of interruptions potentially leading to medical error. There is likely a level at which interruptions are excessive and cause a 'crisis mode' climate.
Methods: We retrospectively collected phone, text messaging, and email interruptions directed to hospital-assigned smartphones on eight General Internal Medicine (GIM) teams at two tertiary care centres in Toronto, Ontario from April 2013 to September 2014. We also calculated the number of times these interruptions exceeded a pre-specified threshold per hour, termed 'crisis mode', defined as at least five interruptions in 30 minutes. We analyzed the correlation between interruptions and date, site, and patient volumes.
Results: A total of 187,049 interruptions were collected over an 18-month period. Daily weekday interruptions rose sharply in the morning, peaking between 11 AM to 12 PM and measuring 4.8 and 3.7 mean interruptions/hour at each site, respectively. Mean daily interruptions per team totaled 46.2 ± 3.6 at Site 1 and 39.2 ± 4.2 at Site 2. The 'crisis mode' threshold was exceeded, on average, 2.3 times/day per GIM team during weekdays. In a multivariable linear regression analysis, site (β6.43 CI95% 5.44 - 7.42, p<0.001), day of the week (with Friday having the most interruptions) (β0.481 CI95% 0.236 - 0.730, p<0.05) and patient census (β1.55 CI95% 1.42 - 1.67, p<0.05) were all predictive of daily interruption volume although there was a significant interaction effect between site and patient census (β-0.941 CI95% -1.18 - -0.703, p<0.05).
Conclusion: Interruptions were related to site-specific features, including volume, suggesting that future interventions should target the culture of individual hospitals. Excessive interruptions may have implications for patient safety especially when exceeding a maximal threshold over short periods of time.
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http://dx.doi.org/10.4338/ACI-2016-08-RA-0130 | DOI Listing |
Nat Cell Biol
January 2025
Beijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, China.
Glucose metabolism has been studied extensively, but the role of glucose-derived excretory glycerol remains unclear. Here we show that hypoxia induces NADH accumulation to promote glycerol excretion and this pathway consumes NADH continuously, thus attenuating its accumulation and reductive stress. Aldolase B accounts for glycerol biosynthesis by forming a complex with glycerol 3-phosphate dehydrogenases GPD1 and GPD1L.
View Article and Find Full Text PDFPLoS Comput Biol
December 2024
Department of Mathematics, University of Manchester, Manchester, United Kingdom.
Understanding the temporal relationship between key events in an individual's infection history is crucial for disease control. Delay data between events, such as infection and symptom onset times, is doubly censored because the exact time at which these key events occur is generally unknown. Current mathematical models for delay distributions are derived from heuristic justifications.
View Article and Find Full Text PDFInt J Radiat Biol
December 2024
Nuclear Engineering Graduate Program, Military Institute of Engineering (IME), Rio de Janeiro, Brazil.
Purpose: This study focuses on analytical computer simulations performed to investigate a hypothetical event where the activation of a radiological dispersion device (RDD) triggers a crisis.
Materials And Methods: The methodology presents steps centered on the initial evaluation phase of the event (initial 100 hours), aiming to evaluate the radiological risks regarding the development of leukemia. Local environmental changes, sex, and age were also used to assess risks.
J ASEAN Fed Endocr Soc
December 2024
Department of Endocrinology, Gauhati Medical College and Hospital, Guwahati, India.
Introduction: Pheochromocytomas are catecholamine-secreting tumors arising from chromaffin cells of the adrenal gland. Surgery is the only curative treatment with a high biochemical cure rate, low mortality and high risk of perioperative complications.
Objectives: To study the demographic characteristics of patients with pheochromocytoma and to identify the risk factors for perioperative complications, treatment outcomes, and aggressive behavior of the tumor.
Pain Manag Nurs
November 2024
Department of Pain Management, Affiliated Hospital of Jiangnan University, Wuxi, China; Department of Internal Medicine, Affiliated Hospital of Jiangnan University, Wuxi, China. Electronic address:
Background: Intrathecal morphine pump helps alleviate pain in the advanced stages of cancer, and thus, ensuring safe intrathecal morphine pump infusion is important. In this study, we investigated the effect of healthcare failure mode and effects analysis (HFMEA) in the management of patients with intrathecal morphine pump implantation.
Methods: We included 112 cancer patients with severe pain who met the inclusion criteria for intrathecal morphine pump implantation treatment in the pain department of our hospital from November 2021 to October 2022.
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