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Novel Mapping Technique for Localization of Focal and Reentrant Activation During Atrial Fibrillation. | LitMetric

AI Article Synopsis

  • The study evaluates a new mapping technology called Ripple Map, used alongside high-density mapping, to improve identification of AF wavefront propagation during ablation procedures in patients with atrial fibrillation (AF).
  • Researchers analyzed electrograms from 45 patients, successfully distinguishing between focal and reentrant activation patterns, finding that Ripple Map was effective in identifying focal activations in 11% of sites.
  • The findings suggest that using Ripple Map for determining ablation targets can lead to a higher rate of atrial fibrillation termination, indicating its potential to enhance patient outcomes in AF ablation.

Article Abstract

Introduction: Identification of wavefront propagation pattern during AF remains challenging in ablation procedures. We sought to test a novel combination of a new mapping technology called Ripple Map and high-density mapping to distinguish focal and reentrant activation during atrial fibrillation (AF).

Methods And Results: Subjects were patients undergoing ablation for persistent AF. If AF remained after isolation of the pulmonary veins, the left atrium (LA) was mapped by a high-density mapping catheter for later analysis, after which ablation was continued using a conventional stepwise approach. After the procedure, electrograms from the high-density mapping catheter were analyzed using Ripple Map, which is a new feature in the CARTO®3, and type of activation on ≥3 consecutive AF cycles was determined. High-density mapping was performed on 569 sites in 45 patients (13 ± 3 sites per patient). AF wavefront propagation determined by Ripple Map was in good agreement with analysis of manual annotation of bipolar electrograms. Ripple Map's representation of wavefront activation pattern, which could include local as well as far-field activity, allowed us to identify focal activation in 64 (11%) sites and 1 (0.2%) reentrant activation site. Radiofrequency delivery in atrial regions with activation sites identified as focal by Ripple Map resulted in termination of AF more often than regions without focal activation (22% vs. 7%, P = 0.015).

Conclusion: This study demonstrated that Ripple Map enabled quick identification of AF wavefront activation pattern, potentially being helpful for determining ablation targets in persistent AF.

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Source
http://dx.doi.org/10.1111/jce.13163DOI Listing

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