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Investigating the Lymphatic Drainage of the Brain: Essential Skills and Tools. | LitMetric

Investigating the Lymphatic Drainage of the Brain: Essential Skills and Tools.

Methods Mol Biol

Clinical Neurosciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK.

Published: January 2018

In this chapter we describe in detail the surgical and imaging techniques employed for the study of the anatomical routes of drainage of cerebrospinal fluid (CSF) and interstitial fluid (ISF) from the brain. The types of tracers, sites of injection, and volumes injected are crucial. For example, when testing the drainage of ISF from the parenchyma, volumes larger than 0.5 μL result in spillage of ISF into the ventricular CSF.

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http://dx.doi.org/10.1007/978-1-4939-6786-5_24DOI Listing

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