The experimental validation of three distinct riboswitch classes has revealed that many bacterial cells naturally produce guanidine, and that living systems have evolved a variety of genes involved in the metabolism and transport of this toxic metabolite. There are numerous biochemical curiosities and mysteries that spring from these advances, which will make for interesting research topics in the coming years.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315402 | PMC |
| http://dx.doi.org/10.1021/acs.biochem.6b01269 | DOI Listing |
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