Herein is reported the mild and general coupling of amine/ether C(sp)-H bonds with various kinds of C(sp)-O electrophiles with high selectivity and efficiency. Valuable allylic/benzylic amines are generated in moderate to excellent yields. The utility of this transformation is demonstrated by a broad substrate scope (>50 examples), good functional group tolerance and facile product modification.
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| http://dx.doi.org/10.1039/c6cc09685a | DOI Listing |
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