AI Article Synopsis
- Ebola virus disease (EVD) poses a significant public health threat with a high death rate and challenges in diagnosis due to symptom overlap with other diseases like malaria and cholera.
- There is currently no quick, reliable, or cost-effective test or treatment for EVD, underscoring the need for improved detection systems.
- The review highlights existing diagnostic methods and emphasizes the need for advancements to ensure effective management during future outbreaks.
Article Abstract
Ebola virus disease (EVD) is a major public health concern with a high mortality rate in infected individuals. Outbreaks of Ebola have been widespread-there is no rapid, sensitive, specific, and affordable diagnostic test for the virus, nor there is any treatment for the disease. Overlapping symptoms of other endemic diseases, such as malaria and cholera, make it difficult to diagnose EVD. For clinical management, outbreak investigation, and proper surveillance, EVD requires a detection system, which should be fast, sensitive, specific, efficient, affordable, and user-friendly with in-country staff. In this review, we discuss the current diagnostics available for Ebola screening, along with the limitations and key improvements necessary for a more robust system to facilitate efficient management in case of another major outbreak.
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| http://dx.doi.org/10.18433/J38C9N | DOI Listing |
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