The toxic effects of diethylketone (DEK) in aqueous solution with different concentrations of Al, Cd, Ni and Mn were evaluated at lab-scale. It was established that Streptococcus equisimilis is able to efficiently remove DEK with different concentrations with heavy metals. It was proved that this joint-system has excellent capacity to biodegrade high concentrations of DEK in the presence of Al, Cd, Ni and Mn. With the exception of Al, the uptake for all metals increased as the initial concentration of each metal in the mixed solution increased. The breakthrough curves are best described by the Adams and Bohart model for Cd, by the Yoon and Nelson model for Ni and by the Wolborska model for Mn.
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