A Rare Case of An Atypical Solitary Fibrous Tumour of Orbit.

J Clin Diagn Res

Professor and Head, Department of Ophthalmology, B.Y.L. Nair Ch. Hopsital , Mumbai, Maharashtra, India .

Published: November 2016

AI Article Synopsis

  • Solitary fibrous tumours are rare growths of mesenchymal origin that usually occur in the pleura but can also develop in various other parts of the body, including the orbit.
  • A case study involving a 41-year-old man showed a painless mass in the left orbit causing eye displacement, with imaging suggesting possible lacrimal gland or nerve sheath tumours.
  • Following complete surgical excision, histopathological results indicated the presence of a solitary fibrous tumour with atypical features; however, no malignant characteristics were found, and the patient remained recurrence-free after 18 months.

Article Abstract

Solitary fibrous tumours are of mesenchymal origin and comprise of uncommon spindle cell neoplasias. Most commonly the lesions arise from pleura but other rarer sites include lungs, peritoneum, pericardium, nasal cavities, thyroid, parotid gland and orbit. We report the case of a 41-year-old male patient who presented to us with a painless, progressive growth of a mass in the superior part of left orbit with proptosis and inferotemporal displacement of the left eye. Computed Tomography (CT) scan revealed homogeneous enhancing lesion in the superior compartment of left orbit in the extraconal region, extending intraconally and distorting the globe. Upon imaging, the differential diagnosis were lacrimal gland tumour, atypical cavernous haemangioma and nerve sheath tumour. Surgical treatment included complete excision of the mass with the intraoperative finding of mass extending upto the superior oblique tendon, a part of which was excised. Histopathological examination revealed CD34 positive, Bcl-2 and MIC-2 positive tumour with the diagnosis of a solitary fibrous tumour with atypical features but no malignant features. After a follow-up of 18 months, no recurrence was detected.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198369PMC
http://dx.doi.org/10.7860/JCDR/2016/21001.8793DOI Listing

Publication Analysis

Top Keywords

solitary fibrous
12
fibrous tumour
8
left orbit
8
tumour atypical
8
tumour
5
rare case
4
case atypical
4
atypical solitary
4
orbit
4
tumour orbit
4

Similar Publications

Introduction: Solitary fibrous bladder tumors are extremely uncommon, with only a few cases reported. These fibroblastic mesenchymal neoplasms are typically benign, indolent, and slow growing.

Case Presentation: A 44-year-old male patient with obstructive uropathy was referred to our unit for workup.

View Article and Find Full Text PDF

Doege Potter syndrome in patient with solitary fibrous tumor of the pleura.

Med J Armed Forces India

December 2024

Senior Resident (Respiratory Medicine), Dr DY Patil Medical College, Hospital & Research Centre, Dr DY Patil Vidyapeeth University, Pune, India.

Solitary fibrous tumors of pleura (SFTP) are rare neoplasms derived from mesenchymal cells of the pleura. A 63-year-old male patient, laborer by profession, presented with progressive dry cough and breathlessness for one month. Clinically he had left-sided intrathoracic mass which was confirmed by CT thorax.

View Article and Find Full Text PDF

Spindle cell lipoma (SCL) is a benign adipocytic tumor usually found in the subcutis of the posterior neck, upper back, and shoulder, predominantly in middle-aged males. This case report describes an atypical presentation of SCL in a 26-year-old male with a history of malignant melanoma. The patient presented with an erythematous plaque with central hyperpigmentation on the right upper arm, an uncommon location and presentation for SCL.

View Article and Find Full Text PDF

Juxtaglomerular cell tumor (JxGCT) is a rare type of renal neoplasm demonstrating morphologic overlap with some mesenchymal tumors such as glomus tumor (GT) and solitary fibrous tumor (SFT). Its oncogenic drivers remain elusive, and only a few cases have been analyzed with modern molecular techniques. In prior studies, loss of chromosomes 9 and 11 appeared to be recurrent.

View Article and Find Full Text PDF

Introduction: The ZAP-X® Gyroscopic Radiosurgery System (ZAP Surgical Systems, Inc., San Carlos, CA, USA) is expected to be a highly accurate next-generation treatment system that enables gyro-stereotactic irradiation of intracranial lesions. In this study, we report the initial treatment course using ZAP-X for intracranial lesions that recurred after Gamma Knife (GK) treatment.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!