[An alternative and innovative Research and Development model to ensure access to medicines - Neglected diseases, neglected populations, and biomedical innovation system].

Med Sci (Paris)

Drugs for Neglected Diseases initiative (DNDi, initiative Médicaments contre les maladies négligées) Chemin Louis-Dunant 15 1202 Genève, Suisse.

Published: December 2016

Download full-text PDF

Source
http://dx.doi.org/10.1051/medsci/20163212001DOI Listing

Publication Analysis

Top Keywords

[an alternative
4
alternative innovative
4
innovative development
4
development model
4
model ensure
4
ensure access
4
access medicines
4
medicines neglected
4
neglected diseases
4
diseases neglected
4

Similar Publications

Nanoscale Metal-Organic Frameworks for the Co-Delivery of Cycloxaprid and Pooled siRNAs to Enhance Control Efficacy in .

J Agric Food Chem

January 2025

China-Kenya Joint Laboratory for Ecological Pest Control of Citrus, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Key Laboratory of Biopesticide and Chemical Biology, MOE, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, China.

RNA pesticides have emerged as a promising alternative to conventional chemical pesticides due to their high specificity and minimal environmental impact. However, the instability of RNA molecules in the environment and the challenges associated with their effective delivery to target pests limit their broader application. This study addresses these challenges by developing a dual delivery system using chitosan (CS) and Metal-Organic Frameworks (MOFs) to enhance the delivery and efficacy of double-stranded RNA (dsRNA) and cycloxaprid against , a vector of citrus greening disease.

View Article and Find Full Text PDF

The use of adjunct chemical substances in the early postoperative period of periodontal surgical procedures is recommended due to the potential risk of trauma in the operated area. Chlorhexidine digluconate mouthwash is widely used but can cause adverse effects. Phthalocyanine derivatives are being studied as an alternative, demonstrating good antimicrobial activity, especially in the self-activated form, which does not require additional light or chemicals.

View Article and Find Full Text PDF

Background: Pulmonary embolism (PE) is a frequent cause of death. Acute PE may be treated either with full anticoagulation (AC) alone or thrombolytic therapy with systemic tissue-- type-plasminogen-activator (tPA) based on risk assessment. Currently, AC is the standard of care for most patients with intermediate-high-risk PE, with low-dose tPA emerging as an effective alternative.

View Article and Find Full Text PDF

Evaluating low NO hydrogen engines designed for off-road and construction applications.

Environ Sci Process Impacts

January 2025

Wolfson Atmospheric Chemistry Laboratories, University of York, Heslington, York, YO10 5DD, UK.

Hydrogen internal combustion engines offer a near-term decarbonisation pathway for hard to electrify sectors such as non-road mobile machinery (NRMM). However, few hydrogen-specific engines have ever been developed with the twin-goals of maximising low carbon energy efficiency and delivering air quality co-benefits. We present analyses of dynamometer-derived nitrogen oxides (NO) tailpipe emissions from four variants of a ∼55 kW four-cylinder port fuelled injection spark ignition hydrogen internal combustion engine (H2ICE) suitable for a range of uses within the NRMM industry.

View Article and Find Full Text PDF

Background The escalating global obesity epidemic requires comprehensive investigations for effective weight management strategies. Understanding the patterns, barriers, and facilitators of dietary interventions is crucial for developing effective weight management protocols. This research aims to assess dietary modification interventions among weight loss subjects in Tamilnadu, South India.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!