Objective: Intracranial aneurysms with an acutely angled parent vessel are difficult to enter using conventional techniques. This study examined efficacy, safety, and technical aspects of intraluminal, intra-aneurysmal, and in vitro microcatheter looping techniques (MLTs).
Methods: MLTs were used to treat intracranial aneurysms with an incorporated acute angle branch in 29 consecutive patients after failed treatment with conventional techniques. The MLT was adopted based on specific morphologic traits of aneurysms and parent vessels. Narrow-necked aneurysms were generally treated with coiling alone, whereas wide-necked aneurysms and giant aneurysms were treated with stent-assisted coiling.
Results: Technical success was achieved in 28 of 29 cases (96.6%). In vitro MLT was used in 12 patients, intraluminal MLT was used in 14 patients, and intra-aneurysmal MLT was used in 3 patients. Immediate total occlusion was achieved in 8 patients, near-total occlusion was achieved in 8 patients, and subtotal occlusion was achieved in 13 patients.
Conclusions: The MLT may provide access to an incorporated, acutely angled arterial branch that is difficult to enter using a conventional coiling technique. The in vitro MLT is potentially safer than intraluminal and intra-aneurysmal MLTs because the loop is very stable and requires less manipulation.
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http://dx.doi.org/10.1016/j.wneu.2016.12.093 | DOI Listing |
Curr Stem Cell Res Ther
January 2025
University Radiology, Rutgers Robert Wood Johnson Medical School Department of Interventional Radiology New Jersey United States.
Vascular stents and stem cells have been used in high-acuity cases for many decades, particularly in cardiology. Providing the physician with another avenue of treatment, they have had a reasonable amount of success. However, there has been very little research conducted on seeding vascular stents with stem cells when treating intracranial aneurysms.
View Article and Find Full Text PDFActa Neurochir (Wien)
January 2025
Division of Neuroradiology and Joint Department of Medical Imaging, University Health Network and Toronto Western Hospital, Toronto, ON, M5T 2S8, Canada.
Purpose: It was noticed that anterior choroidal artery (AChoA) aneurysms appear to rupture at relatively smaller sizes compared with aneurysms in other intracranial locations, based on anecdotal clinical experience. We therefore aimed to compare ruptured AChoA aneurysms with other ruptured aneurysms in other intracranial locations, pertaining to aneurysm dimensions. This may help in finding out if the rupture risk stratification, based on the amalgamation of aneurysms of multiple locations in one group, precisely estimates aneurysm rupture risk.
View Article and Find Full Text PDFAnn Med
December 2025
Department of Neurointervention, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Background: Intracranial aneurysms (IAs) are a significant clinical concern, with detection rates increasing due to advances in imaging technologies. However, precise mechanisms underlying their pathophysiology remain incompletely understood. Recent evidence suggests a pivotal role of oral microbiota dysbiosis, particularly periodontal pathogens, in systemic inflammation that may contribute to IA development and rupture.
View Article and Find Full Text PDFCureus
December 2024
Department of Neurological Surgery, Ryofukai Satoh Neurosurgical Hospital, Fukuyama, Hiroshima, JPN.
Coil embolization of cerebral aneurysms often encounters challenges in achieving complete filling of the aneurysm sac due to complex shapes and hemodynamic factors, frequently resulting in the formation of a residual cavity (RC) at the aneurysm neck. The hemodynamic mechanisms underlying RC formation and growth, however, remain poorly understood. Computational fluid dynamics (CFD) analysis, combined with silent MRA free from contrast agents and metal artifacts, offers a promising approach to elucidate these mechanisms, potentially enhancing the clinical management of cerebral aneurysms post-coiling.
View Article and Find Full Text PDFFront Neurol
December 2024
Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, China.
Background: There are sex disparities in the risk of ruptured intracranial aneurysm (IA), but which sex-specific factors are related to ruptured IA remains inconclusive.
Methods: Data from electronic medical records from two tertiary hospitals, collected between January 2012 and December 2019, were analyzed for this study. All IAs were confirmed by computed tomographic angiography or digital subtraction angiography.
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