Several studies demonstrate that in complex auditory scenes, speech recognition is improved when the competing background and target speech differ linguistically. However, such studies typically utilize spatially co-located speech sources which may not fully capture typical listening conditions. Furthermore, co-located presentation may overestimate the observed benefit of linguistic dissimilarity. The current study examines the effect of spatial separation on linguistic release from masking. Results demonstrate that linguistic release from masking does extend to spatially separated sources. The overall magnitude of the observed effect, however, appears to be diminished relative to the co-located presentation conditions.
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http://dx.doi.org/10.1121/1.4968034 | DOI Listing |
Mol Med
December 2024
Medical Oncology Translational Research Lab, Jilin Cancer Hospital, Changchun, 130012, China.
Background: Small cell lung cancer (SCLC) is a highly fatal malignancy, the complex tumor microenvironment (TME) is a critical factor affecting SCLC progression. Cancer-associated fibroblasts (CAFs) are crucial components of TME, yet their role in SCLC and the underlying mechanisms during their interaction with SCLC cells remain to be determined.
Methods: Microenvironmental cell components were estimated using transcriptome data from SCLC tissue available in public databases, analyzed with bioinformatic algorithms.
Rapid Commun Mass Spectrom
March 2025
US Department of Agriculture, Produce Safety and Microbiology, Western Regional Research Center, Agricultural Research Service, Albany, California, USA.
Rationale: Plasmids can play a major role in the survival of pathogenic bacteria. Plasmids are acquired through horizontal gene transfer resulting in their spread across various strains, species and genera of bacteria. Colicins are bacterial protein toxins expressed by plasmid genes and released against co-located bacterial competitors.
View Article and Find Full Text PDFWest J Emerg Med
November 2024
Indiana University School of Medicine, Department of Emergency Medicine, Indianapolis, Indiana.
Objective: Food insecurity is a prevalent social risk among emergency department (ED) patients. Patients who may benefit from food insecurity resources may be identified via ED-based screening; however, many patients experience difficulty accessing resources after discharge. Co-locating resources in or near the ED may improve utilization by patients, but this approach remains largely unstudied.
View Article and Find Full Text PDFJ Alzheimers Dis
November 2024
Stony Brook World Trade Center Health and Wellness Program, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.
Background: Amyloid-β proteins, a hallmark of Alzheimer's disease, are believed to play an adaptive role in the cerebral immune response.
Objective: Amyloid is believed to play a role in cerebral immune response and could play a similar role in response to air pollution exposures. In the present study, we examined whether WTC exposure duration was associated with cerebral amyloidosis in WTC responders.
Environ Pollut
January 2025
Department of Environmental Medicine and Public Health, and Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, New York, United States.
Ultrafine particles (UFP), commonly expressed as particle number concentrations (PNC), have been associated with harm to human health yet are currently not regulated or routinely monitored in many places. This has limited the potential for studies of health effects of long-term exposure to UFP. The present study aims to understand the spatial and temporal variation in façade-level UFP exposures in Copenhagen, Denmark.
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